Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2020 May-Jun;114(3):446-455.
doi: 10.36660/abc.20190036.

Creation and Implementation of a Prospective and Multicentric Database of Patients with Acute Myocardial Infarction: RIAM

[Article in English, Portuguese]
Jacqueline Vaz  1 , Anibal Pereira Abelin  1   2   3 , Marcia Moura Schmidt  1 , Pedro Piccaro de Oliveira  1 , Carlos A M Gottschall  1 , Clarissa Garcia Rodrigues  1 , Alexandre Schaan de Quadros  1
Affiliations

Creation and Implementation of a Prospective and Multicentric Database of Patients with Acute Myocardial Infarction: RIAM

[Article in English, Portuguese]
Jacqueline Vaz et al. Arq Bras Cardiol. 2020 May-Jun.

Abstract
in English, Portuguese

Background: Multicenter registries representing the real world can be a significant source of information, but few studies exist describing the methodology to implement these tools.

Objective: To describe the process of implementing a database of ST-segment elevation acute myocardial infarction (STEMI) at a reference hospital, and the application of this process to other centers by means of an online platform.

Methods: In 2009, our institution implemented an Registry of Acute Myocardial Infarction (RIAM), with the prospective and consecutive inclusion of every patient admitted to the institution who received a diagnosis of STEMI. From March 2014 to April 2016, the registries were uploaded to a web-based system using the REDCap software and the registry was expanded to other centers. Upon subscription, the REDCap platform is a noncommercial software made available by Vanderbilt University to institutions interested in research.

Results: The following steps were taken to improve and expand the registry: 1. Standardization of variables; 2. Implementation of institutional REDCap (Research Electronic Data Capture); 3. Development of data collection forms (Case Report Form - CRF); 4. Expansion of registry to other reference centers using the REDCap software; 5. Training of teams and participating centers following an SOP (Standard Operating Procedure).

Conclusion: The description of the methodology used to implement and expand the RIAM may help other centers and researchers to conduct similar studies, share information between institutions, develop new health technologies, and assist public policies regarding cardiovascular diseases. (Arq Bras Cardiol. 2020; 114(3):446-455).

Fundamento: Registros multicêntricos representativos do mundo real podem fornecer informações importantes, mas existem poucos estudos descrevendo como implementar estas ferramentas.

Objetivo: Descrever o processo de implementação de um banco de dados em infarto agudo do miocárdio com supradesnivelamento do segmento ST (IAMCST) em um hospital de referência e sua aplicação para outros centros com uma plataforma online .

Métodos: Nossa instituição implementou em 2009 um Registro de Infarto Agudo do Miocárdio (RIAM), com a inclusão prospectiva e consecutiva de todos os pacientes com diagnóstico de IAMCST que internaram na instituição. No período de março de 2014 a abril de 2016 foi realizada a migração para o sistema online com o software REDCap e expansão do registro para outros centros. A plataforma REDCap é um software de uso gratuito disponibilizado pela Universidade Vanderbilt a instituições interessadas em pesquisa, mediante cadastramento prévio.

Resultados: Foram realizadas as seguintes etapas do aprimoramento e expansão do registro: 1. Padronização das variáveis; 2. Implementação do software REDCap ( Research Electronic Data Capture ) institucional; 3. Desenvolvimento de formulários de coleta de dados ( Case Report Form - CRF); 4. Expansão do registro para outros centros de referência utilizando o software REDCap; 5. Treinamento da equipe e dos centros participantes pelo POP (Procedimento Operacional Padrão).

Conclusões: A descrição da metodologia utilizada para implementar e expandir o RIAM pode auxiliar outros centros e pesquisadores a realizar estudos semelhantes, compartilhar informações entre instituições, o desenvolvimento de novas tecnologias em saúde e auxiliar nas políticas públicas em doenças cardiovasculares. (Arq Bras Cardiol. 2020; 114(3):446-455).

PubMed Disclaimer

Conflict of interest statement

Potencial conflito de interesses

Declaro não haver conflito de interesses pertinentes.

Figures

Figura 1
Figura 1. – Fluxograma de aprimoramento e expansão do Registro de Infarto Agudo do Miocárdio Multicêntrico. Fonte: Lucidchart. Disponível em: https://www.lucidchart.com
Figura 2
Figura 2. – Diagrama de opções de criação do Case Report Form. Fonte: REDCap IC/FUC http://redcap.cardiologia.org.br/redcap/redcap_v6.1.0/ProjectSetup/index.php?pid=23
Figura 3
Figura 3. – Distribuição Nacional - Centros do Registro de Infarto Agudo do Miocárdio Multicêntrico. Via: Google Drawings - https://docs.google.com/drawings
Figura 4
Figura 4. – Procedimento Operacional Padrão para inserção de dados no REDCap. Fonte: REDCap IC/FUC - http://redcap.cardiologia.org.br
Figura 5
Figura 5. – Relatório de qualidade de dados. Fonte: REDCap IC/FUC - http://redcap.cardiologia.org.br
Figure 1
Figure 1. – Improvement and expansion flowchart for the multicenter Registry of Acute Myocardial Infarction. Source: Lucidchart. Available in: https://www.lucidchart.com
Figure 2
Figure 2. – Options Diagram for the creation of the Case Report Form. Source: REDCap IC/FUC http://redcap.cardiologia.org.br/redcap/redcap_v6.1.0/ProjectSetup/index.php?pid=23
Figure 4
Figure 4. – Standard Operating Procedure for entering data in REDCap. Source: REDCap IC/FUC - http://redcap.cardiologia.org.br
Figure 5
Figure 5. – Data Quality Report. Source: REDCap IC/FUC - http://redcap.cardiologia.org.br
Figure 3
Figure 3. – National Distribution - Centers of the multicenter Registry of Acute Myocardial Infarction. Via Google Drawings - https://docs.google.com/drawings
See this image and copyright information in PMC

Comment in

References

    1. . Roth GA, Forouzanfar MH, Moran AE, Barber R, Nguyen G, Feigin VL, et al. Demographic and Epidemiologic Drivers of Global Cardiovascular Mortality. N Engl J Med. 2015;372(14):1333–41. - PMC - PubMed
    2. Roth GA, Forouzanfar MH, Moran AE, Barber R, Nguyen G, Feigin VL, et al. Demographic and Epidemiologic Drivers of Global Cardiovascular Mortality. N Engl J Med . 2015;372(14):1333–1341. - PMC - PubMed
    1. . Brasil. Ministério da Saúde. Cadernos de Informação em Saúde. {Citado em 2018 dezembro 27]. Disponível em: ftp://ftp.datasus.gov.br/caderno/geral/br/Brasil_GeralBR.xls.
    2. Brasil. Ministério da Saúde [Citado em 2018 dezembro 27]; Cadernos de Informação em Saúde . ftp://ftp.datasus.gov.br/caderno/geral/br/Brasil_GeralBR.xls.
    1. . Masoudi FA, Ponirakis A, de Lemos JA, Jollis JG, Kremers M, Messenger JC, et al. Trends in U.S. Cardiovascular Care: 2016 Report From 4 ACC National Cardiovascular Data Registries. J Am Coll Cardiol. 2017;69(11):1427–50. - PubMed
    2. Masoudi FA, Ponirakis A, Lemos JA, Jollis JG, Kremers M, Messenger JC, et al. Trends in U.S. Cardiovascular Care: 2016 Report From 4 ACC National Cardiovascular Data Registries. J Am Coll Cardiol . 2017;69(11):1427–1450. - PubMed
    1. . Carruthers KF, Dabbous OH, Flather MD, Starkey I, Jacob A, MacLeod D, et al. Contemporary management of acute coronary syndromes: Does the practice match the evidence? The global registry of acute coronary events (GRACE). Heart. 2005;91(3):290–8. - PMC - PubMed
    2. Carruthers KF, Dabbous OH, Flather MD, Starkey I, Jacob A, MacLeod D, et al. Contemporary management of acute coronary syndromes: Does the practice match the evidence? The global registry of acute coronary events (GRACE) Heart . 2005;91(3):290–298. - PMC - PubMed
    1. . Piegas LS, Avezum Á, Guimarães HP, Muniz AJ, Reis HJL, Santos ES dos, et al. Acute Coronary Syndrome Behavior: Results of a Brazilian Registry. Arq Bras Cardiol. 2013;100(6):502–10. - PubMed
    2. Piegas LS, Avezum Á, Guimarães HP, Muniz AJ, Reis HJL, Santos ES dos, et al. Acute Coronary Syndrome Behavior: Results of a Brazilian Registry. Arq Bras Cardiol . 2013;100(6):502–510. - PubMed