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Editorial
. 2020 Jun;25(6):460-462.
doi: 10.1634/theoncologist.2020-0142. Epub 2020 Apr 17.

The Finding of N-Nitrosodimethylamine in Common Medicines

Richard H Adamson  1 , Bruce A Chabner  2
Affiliations
Editorial

The Finding of N-Nitrosodimethylamine in Common Medicines

Richard H Adamson et al. Oncologist. 2020 Jun.

Abstract

The FDA has ordered the withdrawal of all ranitidine products from the marketplace based on recent findings of increased and unacceptable levels of N‐nitrosodimethylamine (NDMA). This commentary reviews the sources and properties of NDMA, assesses the dangers it poses, and suggests measures to mitigate contamination.

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Figures

Figure 1
Figure 1
The formation of nitrosoamines. For NDMA R1 and R2 are methyl groups.
See this image and copyright information in PMC

References

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