Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Case Reports
. 2020 Aug;39(8):1611-1615.
doi: 10.1007/s10096-020-03880-1. Epub 2020 Apr 8.

A family cluster of severe acute respiratory syndrome coronavirus 2 infections

Xuesong Gao  1 , Zheng Yuan  2 , Di Yang  3 , Hongjie Li  1 , Yijin Zhang  1 , Ping Gao  1 , Xiaomin Liu  4 , Wenshan Zhao  5 , Te Xiao  6 , Xuefei Duan  7
Affiliations
Case Reports

A family cluster of severe acute respiratory syndrome coronavirus 2 infections

Xuesong Gao et al. Eur J Clin Microbiol Infect Dis. 2020 Aug.

Abstract

Clinical and epidemiological knowledge of 2019 novel coronavirus disease (COVID-19) is limited. We reported a family cluster of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) cases in Beijing, China. This family comprised three laboratory confirmed cases with clinical symptoms. All three patients had close contact with a relative from Wuhan, Hubei Province. Throat swab samples were all positive for SARS-CoV-2 using real-time reverse transcriptase-polymerase chain reaction assays. Chest computerized tomography revealed ground-glass opacities and consolidation. SARS-CoV-2 infections tend to clusters. Physicians should be aware of contact history so that infected patients can be identified promptly and further spreading prevented.

PubMed Disclaimer

Conflict of interest statement

The authors declared that they have no competing interests.

Figures

Fig. 1
Fig. 1
Chest CT of patient 1
Fig. 2
Fig. 2
Chest CT of patient 2
Fig. 3
Fig. 3
Chest CT of patient 3
See this image and copyright information in PMC

References

    1. Zhu N, Zhang D, Wang W, et al. A novel coronavirus from patients with pneumonia in China, 2019. N Engl J Med. 2020;382:727–733. doi: 10.1056/NEJMoa2001017. - DOI - PMC - PubMed
    1. World Health Organization (2019) https://www.who.int/emergencies/diseases/ novel-coronavirus-2019. Accessed Feb 20, 2020
    1. World Health Organization (2019). https://www.who.int/docs/default-source/ coronaviruse/situation-reports/20200220-sitrep-31-covid-19.pdf?sfvrsn= dfd11d24_2. Accessed Feb 20, 2020
    1. Chan JF-W, Yuan S, Kok K-H, et al. A familial cluster of pneumonia associated with the 2019 novel coronavirus indicating person-to-person transmission: a study of a family cluster. Lancet. 2020;395:514–523. doi: 10.1016/S0140-6736(20)30154-9. - DOI - PMC - PubMed
    1. Li Q, Guan X, Wu P et al (2020) Early transmission dynamics in Wuhan, China, of novel coronavirus-infected pneumonia. N Engl J Med. 10.1056/NEJMoa2001316 - PMC - PubMed

Publication types

MeSH terms

LinkOut - more resources