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Review
. 2020 Spring;26(2):260-273.
doi: 10.1162/artl_a_00318. Epub 2020 Apr 9.

Engineering Life: A Review of Synthetic Biology

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Review

Engineering Life: A Review of Synthetic Biology

Martin M Hanczyc. Artif Life. 2020 Spring.

Abstract

Synthetic biology is a field of scientific research that applies engineering principles to living organisms and living systems. It is a field that is increasing in scope with respect to organisms engineered, practical outcomes, and systems integration. There is a commercial dimension as well, where living organisms are engineered as green technologies that could offer alternatives to industrial standards in the pharmaceutical and petroleum-based chemical industries. This review attempts to provide an introduction to this field as well as a consideration of important contributions that exemplify how synthetic biology may be commensurate or even disproportionate with the complexity of living systems. The engineerability of living systems remains a difficult task, yet advancements are reported at an ever-increasing pace.

Keywords: Synthetic biology; artificial cell; genetic engineering; metabolic engineering.

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