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Review
. 2020 Jul:191:110996.
doi: 10.1016/j.colsurfb.2020.110996. Epub 2020 Mar 29.

The role of magnesium in biomaterials related infections

Verónica Luque-Agudo  1 , M Coronada Fernández-Calderón  2 , Miguel A Pacha-Olivenza  3 , Ciro Pérez-Giraldo  4 , Amparo M Gallardo-Moreno  5 , M Luisa González-Martín  1
Affiliations
Review

The role of magnesium in biomaterials related infections

Verónica Luque-Agudo et al. Colloids Surf B Biointerfaces. 2020 Jul.

Abstract

Magnesium is currently increasing interest in the field of biomaterials. An extensive bibliography on this material in the last two decades arises from its potential for the development of biodegradable implants. In addition, many researches, motivated by this progress, have analyzed the performance of magnesium in both in vitro and in vivo assays with gram-positive and gram-negative bacteria in a very broad range of conditions. This review explores the extensive literature in recent years on magnesium in biomaterials-related infections, and discusses the mechanisms of the Mg action on bacteria, as well as the competition of Mg2+ and/or synergy with other divalent cations in this subject.

Keywords: bacteria; biomaterial; infection; magnesium.

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Conflict of interest statement

Declaration of Competing Interest X The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.

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