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. 2020 May 8;12(5):e12481.
doi: 10.15252/emmm.202012481. Epub 2020 Apr 28.

Why does Japan have so few cases of COVID-19?

Akiko Iwasaki  1   2 , Nathan D Grubaugh  3
Affiliations

Why does Japan have so few cases of COVID-19?

Akiko Iwasaki et al. EMBO Mol Med. .

Abstract

The COVID-19 pandemic has spread to many countries around the world, but the infection and death rates vary widely. One country that appeared to have kept the infection under control despite limited societal restrictions is Japan. This commentary explores why Japan may have, up to now, been spared an escalation of the SARS-CoV-2 infections.

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Figures

Figure 1
Figure 1. Cumulative number of cases, by number of days since February 1, 2020
Source: https://ourworldindata.org/coronavirus#confirmed-covid-19-deaths-by-country, accessed 6‐4‐2020, data based on European Centre for Disease Prevention and Control.
See this image and copyright information in PMC

Comment in

References

    1. Arts RJW, Moorlag S, Novakovic B, Li Y, Wang SY, Oosting M, Kumar V, Xavier RJ, Wijmenga C, Joosten LAB et al (2018) BCG Vaccination Protects against Experimental Viral Infection in Humans through the Induction of Cytokines Associated with Trained Immunity. Cell Host Microbe 23: 89–100.e5 - PubMed
    1. Boelle PY, Ansart S, Cori A, Valleron AJ (2011) Transmission parameters of the A/H1N1 (2009) influenza virus pandemic: a review. Influenza Other Respir Viruses 5: 306–316 - PMC - PubMed
    1. Cao Y, Li L, Feng Z, Wan S, Huang P, Sun X, Wen F, Huang X, Ning G, Wang W (2020) Comparative genetic analysis of the novel coronavirus (2019‐nCoV/SARS‐CoV‐2) receptor ACE2 in different populations. Cell Discov 6: 11 - PMC - PubMed
    1. Hadfield J, Megill C, Bell SM, Huddleston J, Potter B, Callender C, Sagulenko P, Bedford T, Neher RA (2018) Nextstrain: real‐time tracking of pathogen evolution. Bioinformatics 34: 4121–4123 - PMC - PubMed
    1. Higgins JP, Soares‐Weiser K, Lopez‐Lopez JA, Kakourou A, Chaplin K, Christensen H, Martin NK, Sterne JA, Reingold AL (2016) Association of BCG, DTP, and measles containing vaccines with childhood mortality: systematic review. BMJ 355: i5170 - PMC - PubMed

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