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. 2020 Jul:141:55-59.
doi: 10.1016/j.urology.2020.03.019. Epub 2020 Apr 8.

Role of Diffusion-Weighted Magnetic Resonance Imaging in the Diagnosis of Bladder Pain Syndrome/Interstitial Cystitis

Porru Daniele  1 , Regina Cesare  2 , Oworae Howardson Bright  2 , Fiorello Nicolo  2 , Gardella Barbara  3 , Manzoni Federica  4 , Klersy Catherine  4 , Sala Maria Gabriella  5 , La Fianza Alfredo  5 , Ballerini Daniela  5 , Preda Lorenzo  5 , Simeone Claudio  6 , Spinillo Arsenio  3 , Jallous Hussein  2
Affiliations

Role of Diffusion-Weighted Magnetic Resonance Imaging in the Diagnosis of Bladder Pain Syndrome/Interstitial Cystitis

Porru Daniele et al. Urology. 2020 Jul.

Abstract

Some recent studies evaluated the introduction of diffusion-weighted magnetic resonance imaging (DW-MRI) in the diagnosis of bladder pain syndrome/interstitial cystitis (BPS/IC).

Objective: To evaluate whether DW-MRI can contribute to noninvasive diagnosis of BPS/IC. The agreement between two raters (2 radiologists involved in the study) was also evaluated, the relevance of the "operator-dependent" factor defined.

Patients and methods: Twenty-two female patients with a diagnosis of BPS-IC were recruited and performed DW-MRI. The same investigation was also performed in 20 patients with pelvic gynecological diseases and no BPS-IC.

Results: A significant difference was found between BPS-IC and no-BPS-IC since 17 out of 22 subjects of the first group were positive, compared to 3 out of 20 no-IC subjects, with a P value of .001 to highlight the statistical significance. The sensitivity of the exam was 77%, while the specificity was 85%. There was good agreement between the 2 raters in the evaluation of MRI results.

Conclusion: DW-MRI helps to obtain a noninvasive diagnosis of BPS/IC, by providing useful information on the choice of which patients may be more appropriately submitted to cystoscopy and bladder biopsy.

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