An Overview of the Current State and the Future of Ataxia Treatments
- PMID: 32279720
- PMCID: PMC7220524
- DOI: 10.1016/j.ncl.2020.01.008
An Overview of the Current State and the Future of Ataxia Treatments
Abstract
Cerebellar ataxia can be caused by a variety of disorders, including degenerative processes, autoimmune and paraneoplastic illness as well as by gene mutations inherited in autosomal dominant, autosomal recessive, or X-linked fashions. In this review, we highlight the treatments for cerebellar ataxia in a systematic way, to provide guidance for clinicians who treat patients with cerebellar ataxia. In addition, we review therapies currently under development for ataxia, which we feel is currently one of the most exciting fields in neurology.
Keywords: Ataxia; Ataxia treatment; Cerebellum; Friedreich ataxia; Multiple system atrophy; Spinocerebellar ataxia.
Copyright © 2020 Elsevier Inc. All rights reserved.
Conflict of interest statement
Disclosure The authors have no relationship with a commercial company that has a direct financial interest in the subject matter or materials discussed in this article or with a company making a competing product.
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References
-
- Stoodley CJ, Schmahmann JD. Functional topography of the human cerebellum. Handb Clin Neurol. 2018;154:59–70. - PubMed
-
- Ruano L, Melo C, Silva MC, Coutinho P. The global epidemiology of hereditary ataxia and spastic paraplegia: A systematic review of prevalence studies. Neuroepidemiology. 2014;42(3):174–183. - PubMed
-
- Klockgether T Sporadic ataxia with adult onset: Classification and diagnostic criteria. Lancet Neurol. 2010;9(1):94–104. - PubMed
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