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. 2020 Apr 6;6(1):00054-2020.
doi: 10.1183/23120541.00054-2020. eCollection 2020 Jan.

Diurnal variation in forced vital capacity in patients with fibrotic interstitial lung disease using home spirometry

Affiliations

Diurnal variation in forced vital capacity in patients with fibrotic interstitial lung disease using home spirometry

Catharina C Moor et al. ERJ Open Res. .

Abstract

This study demonstrates a diurnal variation in FVC measured with home spirometry in patients with f-ILD, with a higher FVC in the morning than in the afternoon http://bit.ly/37SQtBK.

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Conflict of interest statement

Conflict of interest: C.C. Moor reports grants and support from Boehringer Ingelheim outside the submitted work. Conflict of interest: C.A.L. van den Berg has nothing to disclose. Conflict of interest: L.S. Visser has nothing to disclose. Conflict of interest: J.G.J.V. Aerts has nothing to disclose. Conflict of interest: V. Cottin reports personal fees and nonfinancial support for advisory boards, lectures and travel to medical meetings from Actelion; grants, personal fees and nonfinancial support for consultancy, lectures and travel to medical meetings from Boehringer Ingelheim; personal fees for advisory boards and membership of a data safety monitoring boards (DSMB) from Bayer/MSD; personal fees for advisory boards and lectures from Novartis; personal fees and nonfinancial support for consultancy, lectures and travel to medical meetings from Roche; personal fees for lectures from Sanofi, personal fees for chairing as DSMB and membership of a steering committee from Promedior; personal fees for membership of a DSMB from Celgene; personal fees for advisory boards and cochairing a DSMB from Galapagos; and personal fees for membership of a DSMB from Galecto, all outside the submitted work. Conflict of interest: M.S. Wijsenbeek reports grants and other support from Hoffman-la Roche and Boehringer Ingelheim, and other support from Galapagos, all paid to her institution and all outside the submitted work.

Figures

FIGURE 1
FIGURE 1
a) Differences in forced vital capacity (FVC) between morning and afternoon for individual patients. b) Differences in steps per hour before morning and afternoon FVC measurement.

References

    1. Raghu G, Collard HR, Egan JJ, et al. An official ATS/ERS/JRS/ALAT statement: idiopathic pulmonary fibrosis: evidence-based guidelines for diagnosis and management. Am J Respir Crit Care Med 2011; 183: 788–824. doi: 10.1164/rccm.2009-040GL - DOI - PMC - PubMed
    1. Maher TM, Kreuter M, Lederer DJ, et al. Rationale, design and objectives of two phase III, randomised, placebo-controlled studies of GLPG1690, a novel autotaxin inhibitor, in idiopathic pulmonary fibrosis (ISABELA 1 and 2). BMJ Open Respir Res 2019; 6: e000422. doi: 10.1136/bmjresp-2019-000422 - DOI - PMC - PubMed
    1. Distler O, Highland KB, Gahlemann M, et al. Nintedanib for systemic sclerosis-associated interstitial lung disease. N Engl J Med 2019; 380: 2518–2528. doi: 10.1056/NEJMoa1903076 - DOI - PubMed
    1. Hetzel MR. The pulmonary clock. Thorax 1981; 36: 481–486. doi: 10.1136/thx.36.7.481 - DOI - PMC - PubMed
    1. Medarov BI, Pavlov VA, Rossoff L. Diurnal variations in human pulmonary function. Int J Clin Exp Med 2008; 1: 267–273. - PMC - PubMed

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