Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2020 Jul;75(7):1809-1812.
doi: 10.1111/all.14316. Epub 2020 Apr 27.

Distinct characteristics of COVID-19 patients with initial rRT-PCR-positive and rRT-PCR-negative results for SARS-CoV-2

Jin-Jin Zhang  1 , Yi-Yuan Cao  2 , Xiang Dong  1 , Bin-Chen Wang  2 , Mei-Yan Liao  2 , Jun Lin  3 , You-Qin Yan  4 , Cezmi A Akdis  5 , Ya-Dong Gao  1
Affiliations

Distinct characteristics of COVID-19 patients with initial rRT-PCR-positive and rRT-PCR-negative results for SARS-CoV-2

Jin-Jin Zhang et al. Allergy. 2020 Jul.
No abstract available

PubMed Disclaimer

Conflict of interest statement

The authors have no conflict of interest.

Figures

Figure 1
Figure 1
Number of patients testing positive for SARS‐CoV‐2 and the cumulative positive ratio at different rRT‐PCR tests. A, Changes in the outcome of the rRT‐PCR test of patients, from negative to positive, after consecutive assays. Of the 41 patients with an initial negative result, 21, 13, 4, 2, and 1 patients were tested positive at the 2nd, 3rd, 4th, 5th, and 6th rRT‐PCR assays, respectively. The cumulative positive rRT‐PCR assay ratio from the second to the fifth test increased from 51.2% (21/41) to 97.6% (40/41). B, Number and percentage of positive results within the total patient population. The cumulative positive ratio of all 290 patients from the first to the fifth test increased from 85.9% (249/290) to 99.7% (289/290). rRT‐PCR, real‐time reverse transcription–polymerase chain reaction
See this image and copyright information in PMC

References

    1. World Health Organization (WHO) . Coronavirus disease (COVID‐2019) situation reports. https://www.who.int/emergencies/diseases/novel‐coronavirus‐2019/situatio.... Accessed March 17, 2020.
    1. World Health Organization (WHO) . Laboratory testing for 2019 novel coronavirus (2019‐nCoV) in suspected human cases. Interim guidance. Published March 2, 2020. https://www.who.int/publications‐detail/laboratory‐testing‐for‐2019‐nove.... Accessed March 16, 2020.
    1. Huang P, Liu T, Huang L, et al. Use of chest CT in combination with Negative RT‐PCR assay for the 2019 novel coronavirus but high clinical suspicion. Radiology. 2020;295:22‐23. - PMC - PubMed
    1. Xie X, Zhong Z, Zhao W, Zheng C, Wang F, Liu J. Chest CT for typical 2019‐nCoV pneumonia: relationship to negative RT‐PCR Testing. Radiology. 2020;200343. 10.1148/radiol.2020200343 [Epub ahead of print]. - DOI - PMC - PubMed
    1. Peiris JS, Chu CM, Cheng VC, et al. Clinical progression and viral load in a community outbreak of coronavirus‐associated SARS pneumonia: a prospective study. Lancet. 2003;361:1767‐1772. - PMC - PubMed

MeSH terms