Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2020 Apr 13;14(4):e0008184.
doi: 10.1371/journal.pntd.0008184. eCollection 2020 Apr.

The Strongyloides stercoralis-hookworms association as a path to the estimation of the global burden of strongyloidiasis: A systematic review

Pedro E Fleitas  1   2 , Marina Travacio  3 , Helena Martí-Soler  4 , M Eugenia Socías  5 , Walter R Lopez  1 , Alejandro J Krolewiecki  1   4
Affiliations

The Strongyloides stercoralis-hookworms association as a path to the estimation of the global burden of strongyloidiasis: A systematic review

Pedro E Fleitas et al. PLoS Negl Trop Dis. .

Abstract

PROSPERO (registration code CRD42019131127).

PubMed Disclaimer

Conflict of interest statement

The authors have declared that no competing interests exist.

Figures

Fig 1
Fig 1. PRISMA (preferred reporting items for systematic reviews and meta-analyses) flow diagram of systematic literature search.
Fig 2
Fig 2. Map of the geographical distribution of the included surveys (n = 127) [20].
The size of each circle is proportional to the total number of surveyed individuals in each country. Countries are represented in green (community based surveys) or orange (school-aged children). Countries with both type of surveys are represented in green and orange bars.
Fig 3
Fig 3. Number of surveys per year.
Orange bars represent the number of surveys in school-aged children (SAC) population. Green bars represent the number of surveys of the Community population. The blue line represents the total number of surveys with highly sensitive diagnostic methods (High-S).
Fig 4
Fig 4. Spline of different surveys weighted by sample size.
a. In black dots and green line all Community based surveys. b. In black dots and orange line: school-aged children (SAC) based surveys. The size of all dots is proportional to the sample size.
Fig 5
Fig 5. Linear regression.
Blue dots represent surveys with high sensitivity diagnostic methods (Hight-S) and purple dots represent surveys with low sensitivity diagnostic methods (Low-S). a. Community surveys. The black line represents the curve of equation 1 (Table 1), for the linear regression of all surveys (Hight-S and Low-S) of the Community population. The blue line represents the curve of equation 2 (Table 1), for the linear regression of all surveys of the Community population with Hight-S. b. School-aged children (SAC) surveys. The black line represents the curve of equation 3 (Table 1), for the linear regression of all surveys (Hight-S and Low-S) of the SAC population. The blue line represents the curve of equation 4 (Table 1), for the linear regression of all surveys of the SAC population with Hight-S. Gray shading represents the 95% confidence interval.
See this image and copyright information in PMC

References

    1. World Health Assembly, 54. (‎2001)‎. Schistosomiasis and soil-transmitted helminth infections. World Health Organization; Available from: https://apps.who.int/iris/handle/10665/78794.
    1. WHO. Schistosomiasis and soil-transmittes helminthiases: numbers of people treated in 2017. Wkly Epidemiol Rec. 2018;50:681–92. Available from: https://www.who.int/neglected_diseases/resources/who_wer9350/en/ - PubMed
    1. Streit A. Reproduction in Strongyloides (Nematoda): a life between sex and parthenogenesis. Parasitology. 2008;135:285–94. 10.1017/S003118200700399X - DOI - PubMed
    1. WHO‎. 2030 targets for soil-transmitted helminthiases control programmes. World Health Organization. WHO; 2020. Available from: https://apps.who.int/iris/handle/10665/330611.
    1. Olsen A, van Lieshout L, Marti H, Polderman T, Polman K, Steinmann P, et al. Strongyloidiasis—the most neglected of the neglected tropical diseases? Trans R Soc Trop Med Hyg. 2009;103:967–72. 10.1016/j.trstmh.2009.02.013 - DOI - PubMed

Publication types

MeSH terms