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Case Reports
. 2020 Jul;95(7):876-878.
doi: 10.1002/ajh.25833. Epub 2020 May 12.

Rapid and severe Covid-19 pneumonia with severe acute chest syndrome in a sickle cell patient successfully treated with tocilizumab

Affiliations
Case Reports

Rapid and severe Covid-19 pneumonia with severe acute chest syndrome in a sickle cell patient successfully treated with tocilizumab

Gonzalo De Luna et al. Am J Hematol. 2020 Jul.
No abstract available

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Conflict of interest statement

Bartolucci reports being a consultant for F. Hoffmann‐La Roche. No other potential conflict of interest relevant to this letter was reported.

Figures

IMAGE 1
IMAGE 1
CT scan of the chest: Acute chest syndrome and Covid‐19‐induced pneumonia. A, Axial image of chest obtained with a soft‐tissue windows at the level of the lower lobes evidenced areas of consolidation located at the posterior part of the lung (arrows). B, An axial image with the same windowing obtained at the upper part of the lungs showed a right small pleural effusion in the upper part of the great pleural cavity (arrow). C, Axial image located at the same level as A with lung windows evidenced areas of ground‐glass opacities (arrows) in the lower lungs with regards to areas of consolidation, but also in the middle lobe (arrowhead) D, and in the upper right lobe. E, Coronal reconstruction confirmed areas of ground‐glass opacities (arrow) and areas of consolidation with air bronchograms (arrowhead). F, Magnification of a CT image with lung windows acquired at the middle part of the lungs showing a crazy‐paving pattern with ground‐glass opacities and interlobar septal thickening (arrowhead)

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References

    1. Bulletin épidémiologique hebdomadaire [Internet]. http://beh.santepubliquefrance.fr/beh/2015/8/2015_8_2.html. Accessed April 3, 2020.
    1. Vichinsky EP, Neumayr LD, Earles AN, et al. Causes and outcomes of the acute chest syndrome in sickle cell disease. National Acute Chest Syndrome Study Group. N Engl J Med. 2000;342(25):1855‐1865. - PubMed
    1. Bundy DG, Strouse JJ, Casella JF, Miller MR. Burden of influenza‐related hospitalizations among children with sickle cell disease. Pediatrics. 2010;125(2):234‐243. - PMC - PubMed
    1. Strouse JJ, Reller ME, Bundy DG, et al. Severe pandemic H1N1 and seasonal influenza in children and young adults with sickle cell disease. Blood. 2010;116(18):3431‐3434. - PMC - PubMed
    1. Boissier F, Bagate F, Schmidt M, et al. Extracorporeal Life Support for Severe Acute Chest Syndrome in Adult Sickle Cell Disease: A Preliminary Report. Crit Care Med. 2019;47(3):e263‐e265. - PubMed

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