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Review
. 2020 Aug 26;50(5):1480-1490.
doi: 10.3906/sag-1912-197.

Omics era in forensic medicine: towards a new age

Ramazan Akçan  1 , Burak Taştekin  1 , Mahmut Şerif Yildirim  2 , Halit Canberk Aydogan  1 , Necdet Sağlam  3
Affiliations
Review

Omics era in forensic medicine: towards a new age

Ramazan Akçan et al. Turk J Med Sci. .

Abstract

Background/aim: Forensic medicine and sciences is a multidisciplinary branch of science, which frequently benefit from novel technologies. State of the art omics technologies have begun to be performed in forensic medicine and sciences, particularly in postmortem interval, intoxication, drugs of abuse, diagnosis of diseases and cause of death. This review aims to discuss the role and use of great omics (metabolomics, proteomics, genomics and transcriptomics) in forensic sciences, in detail.

Materials and methods: A detailed review of related literature was performed, and studies were subdivided as per the type of omics.

Results and conclusion: Omics seems as a revolutionary step in forensic science and sure carries it towards a new age. The number of forensic studies utilizing omics steadily increases in last years. Omics strategies should be used together in order to gather more accurate and certain data. Additional studies need to be performed to incorporate omics into routine forensic methodology.

Keywords: Forensic medicine/science; drugs of abuse; omics; post-mortem interval.

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Conflict of interest statement

There is no conflict of interest between the authors concerning the materials or methods used in this study or the findings specified in this paper.

Figures

Figure
Figure
General scheme of relationship between omics and phenotype.
See this image and copyright information in PMC

References

    1. Parikh’s textbook of medical jurisprudence, forensic medicine and toxicology. 6th ed. New Delhi, India: CBS Publishers. 1999.
    1. Yadav SP The wholeness in suffix -omics, -omes, and the word om. Journal of Biomolecular Techniques . 2007;18:277–277. - PMC - PubMed
    1. Donaldson AE Lamont IL Estimation of post-mortem interval using biochemical markers. Australian Journal of Forensic Sciences . 2013;46:8–26.
    1. Giebultowicz J Ruzycka M Fudalej M Krajewski P Wroczynski P LC-MS/MS method development and validation for quantitative analyses of 2-aminothiazoline-4-carboxylic acid--a new cyanide exposure marker in post mortem blood. Talanta . 2016;150:586–592. - PubMed
    1. Tsai IL Weng TI Tseng YJ Tan HK Sun HJ Screening and confirmation of 62 drugs of abuse and metabolites in urine by ultra-high-performance liquid chromatography-quadrupole time-of-flight mass spectrometry. Journal of Analytical Toxicology . 2013;37:642–651. - PubMed

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