Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2020:1229:259-271.
doi: 10.1007/978-981-15-1671-9_15.

Non-coding RNAs and Ischemic Cardiovascular Diseases

Tarik Smani  1   2 , Isabel Mayoral-Gonzalez  3   4 , Isabel Galeano-Otero  3 , Isabel Gallardo-Castillo  5 , Juan A Rosado  6 , Antonio Ordoñez  3   4   7 , Abdelkrim Hmadcha  8
Affiliations
Review

Non-coding RNAs and Ischemic Cardiovascular Diseases

Tarik Smani et al. Adv Exp Med Biol. 2020.

Abstract

The Ischemic Heart Disease (IHD) is considered a clinical condition characterized by myocardial ischemia causing an imbalance between myocardial blood supply and demand, leading to morbidity and mortality across the worldwide. Prompt diagnostic and prognostic represents key factors for the treatment and reduction of the mortality rate. Therefore, one of the newest frontiers in cardiovascular research is related to non-coding RNAs (ncRNAs), which prompted a huge interest in exploring ncRNAs candidates for utilization as potential therapeutic targets for diagnostic and prognostic and/or biomarkers in IHD. However, there are undoubtedly many more functional ncRNAs yet to be discovered and characterized. Here we will discuss our current knowledge and we will provide insight on the roles and effects elicited by some ncRNAs related to IHD.

Keywords: Cardioprotection; Ischemia and reperfusion; Non-coding RNAs; RNAs.

PubMed Disclaimer

LinkOut - more resources