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. 2016 Oct;65(4):831-839.
doi: 10.1016/j.ejcdt.2016.06.002. Epub 2016 Jun 18.

Clinical presentations and outcome of severe community-acquired pneumonia

Mousa Elshamly  1 , Mohamed O Nour  2 , Abdelmaaboud M M Omar  3
Affiliations

Clinical presentations and outcome of severe community-acquired pneumonia

Mousa Elshamly et al. Egypt J Chest Dis Tuberc. 2016 Oct.

Abstract

Background: Severe community-acquired pneumonia (SCAP) represents a frequent and potentially life-threatening condition. About 10% of all hospitalized patients with CAP require admission to the intensive care unit (ICU), and the mortality of these patients reaches 20-50%.

Objective: To evaluate the clinical presentation, bacteriological profile and outcome of severe community-acquired pneumonia (SCAP).

Patients and methods: 54 patients presented by symptoms and sign of severe community acquired pneumonia who were admitted to respiratory care unit of Alhussein, Al-Azhar University Hospital from August 2015 to March 2016 were subjected to full clinical examination, chest X ray, complete blood picture, sputum and blood culture, PCR for suspected cases of Influenza H1N1 and MERS-COV, treatment, follow up, data collections and statistical analysis.

Results: The present study included 54 patients 26 males and 28 females with SCAP who were admitted to respiratory care unit of Alhussein, Al-Azhar University Hospital. The most common comorbidities were diabetes mellitus and hypertension. The most common presentations were fever, cough, dyspnea and hypoxemia. Two patients developed renal failure and 4 patients developed septic shock. The most common isolated organism was Streptococcus pneumoniae, Influenza H1N1, and Staphylococcus aureus. Mortality was 24% and it was common in patients with comorbidity than in patients without comorbidities.

Conclusion: SCAP occurs more frequently in those with comorbidities. The most frequent isolated causative organism of SCAP is S. pneumoniae, Influenza H1N1 and S. aureus. SCAP is associated with significant mortality, early recognition and prompt treatment may improve outcome.

Keywords: Outcome; Presentation; Severe community acquired pneumonia.

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Figures

Figure 1
Figure 1
Chest X ray of 40 year old female with severe CAP.
Figure 2
Figure 2
Chest X ray of 35 year old male with severe CAP.
Figure 3
Figure 3
Chest X ray of 38 year female with severe CAP.
Figure 4
Figure 4
CT chest of 53 year male patient with severe CAP.
See this image and copyright information in PMC

References

    1. Marik P.E. Norasept II Study Investigators. The clinical features of severe community-acquired pneumonia presenting as septic shock. J. Crit. Care. 2000;15(3):85–90. - PubMed
    1. Health and Welfare Statistics Association of Japan Annual report of national health and hygiene in Japan. Kouseinoshihyou. 2004;51:382–385. (in Japanese)
    1. Lim W.S., Baudouin S.V., George R.C., Hill A.T., Jamieson J., Le Jeune, Macfarlane J.T., Read R.C., Roberts H.J., Levy M.L., Wani M., Woodhead M.A. BTS guidelines for the management of community acquired pneumonia in adults: update 2009. Thorax. 2009;64(III) iii1–iii55. 2. - PubMed
    1. File T.M. Community-acquired pneumonia. Lancet. 2003;362:1991–2001. - PMC - PubMed
    1. Fang G.D., Fine M., Orloff J., Arisumi D., Yu V.L., Kapoor W., Grayston T., Wang S.P., Kohler R., Muder R., Ying Y.C., Rihs J.D., Vickers R.M. New and emerging etiologies for community-acquired pneumonia with implications for therapy: a prospective multicenter study of 359 cases. Medicine. 1990;69:307–316. - PubMed

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