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. 2012 Jul;21(3):264-269.
doi: 10.1053/j.jepm.2012.06.001. Epub 2012 Jul 30.

Diagnostic Challenge

Miriam M Shanaman  1 , Mark A Mitchell  1 , Samantha Haskins  1 , Ken Welle  1 , Zoltan Demeter  1 , Shih-Hsuan Hsiao  1 , Sandra Murrell-Ritter  1 , Robert T O'Brien  1
Affiliations

Diagnostic Challenge

Miriam M Shanaman et al. J Exot Pet Med. 2012 Jul.
No abstract available

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Figures

FIGURE 1
FIGURE 1
Right lateral whole-body radiograph.
FIGURE 2
FIGURE 2
Ventrodorsal whole-body radiograph.
FIGURE 3
FIGURE 3
Right lateral whole-body radiograph. Note the soft tissue opaque mass (*) in the cranioventral thorax resulting in dorsal tracheal displacement and caudodorsal displacement of the cardiac silhouette. An enlarged, rounded splenic tail can be seen lining the caudoventral abdominal cavity (arrow).
FIGURE 4
FIGURE 4
Ventrodorsal whole-body radiograph. Note the soft tissue opaque mass effect occupying the width of the cranial thoracic cavity along midline (between arrows).
FIGURE 5
FIGURE 5
Sagittal plane CT reconstruction of the thorax displayed in a soft tissue window post-administration of contrast medium. Note the intimate association of the cranial mediastinal mass lesion with the major thoracic vasculature (arrow). An enlarged, rounded sternal lymph node can be seen dorsal to the level of the second sternebra (*).
FIGURE 6
FIGURE 6
Dorsal plane 3D-volume–rendering CT obtained in the same postcontrast phase as in Figure 5. The sternebrae have been cropped to permit visualization of the ventral surface of the cardiac silhouette and cranial mediastinal mass. The cranial mediastinal mass is displayed in a bluish hue; note the marked tortuous vasculature embedded within the mass and intimate association of the mass with the adjacent cardiac silhouette and thoracic aorta.
FIGURE 7
FIGURE 7
Histologic section of cranial mediastinum from a ferret with multisystemic coronavirus infection (ferret FIP). Cranial mediastinum is infiltrated by densely cellular, coalescing aggregates of epithelioid and foamy macrophages with interspersed lymphocytes, plasma cells, and neutrophils (granulomatous mediastinitis). Hematoxylin and eosin stain.
FIGURE 8
FIGURE 8
Histologic section of cranial mediastinum from a ferret with multisystemic coronavirus infection (ferret FIP). Intralesional coronavirus are positively labeled by immunohistochemistry with an antibody specific for ferret coronavirus (Custom Monoclonals International). Avidin-biotin complex method, hematoxylin counterstain.
See this image and copyright information in PMC

References

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