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. 2020 Feb;7(2):239-242.
doi: 10.1093/nsr/nwaa009. Epub 2020 Jan 29.

Evolutionary perspectives on novel coronaviruses identified in pneumonia cases in China

Affiliations

Evolutionary perspectives on novel coronaviruses identified in pneumonia cases in China

Xiaoman Wei et al. Natl Sci Rev. 2020 Feb.
No abstract available

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Figures

Figure 1.
Figure 1.
Simplified phylogeny of 2b subgroup in Betacoronavirus genus. This phylogenetic tree shows the genetic background and phylogenetics of this virus, as drawn from published findings. Subgenus was also shown for purpose of clustering only. The host figures are used to infer the origin of the viruses, and the host in gray indicates the new virus – SARS-CoV-2 discovered in Wuhan. The information of viral receptors [DPP4 (dipeptidyl peptidase-4) or ACE2 (angiotensin-converting enzyme 2)] is also shown for Merbecovirus and Sarbecovirus where ‘?’ indicates ‘an unidentified receptor’.
Figure 2.
Figure 2.
Putative model of evolution and transmission of pathogenic coronaviruses. Different color-coded coronaviruses on the top circle represent progenitors in natural reservoirs of different bats. Coronaviruses shown in mixed colors represent generated recombinants, which potentially lead to the cross-species transmission to other animals (intermediate hosts) or humans (end hosts).

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