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Review
. 2015 Jun;4(2):119-133.
doi: 10.1016/j.bjbas.2015.05.004. Epub 2015 May 16.

A review on versatile applications of transition metal complexes incorporating Schiff bases

Ahmed M Abu-Dief  1   2 , Ibrahim M A Mohamed  1
Affiliations
Review

A review on versatile applications of transition metal complexes incorporating Schiff bases

Ahmed M Abu-Dief et al. Beni Suef Univ J Basic Appl Sci. 2015 Jun.

Abstract

Schiff bases and their complexes are versatile compounds synthesized from the condensation of an amino compound with carbonyl compounds and widely used for industrial purposes and also exhibit a broad range of biological activities including antifungal, antibacterial, antimalarial, antiproliferative, anti-inflammatory, antiviral, and antipyretic properties. Many Schiff base complexes show excellent catalytic activity in various reactions and in the presence of moisture. Over the past few years, there have been many reports on their applications in homogeneous and heterogeneous catalysis. The high thermal and moisture stabilities of many Schiff base complexes were useful attributes for their application as catalysts in reactions involving at high temperatures. The activity is usually increased by complexation therefore to understand the properties of both ligands and metal can lead to the synthesis of highly active compounds. The influence of certain metals on the biological activity of these compounds and their intrinsic chemical interest as multidentate ligands has prompted a considerable increase in the study of their coordination behaviour. Development of a new chemotherapeutic Schiff bases and their metal complexes is now attracting the attention of medicinal chemists. This review compiles examples of the most promising applied Schiff bases and their complexes in different areas.

Keywords: Antimicrobial; Bio-inorganic chemistry; Catalysis; Complex; Dyes; Polymers; Schiff base.

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Figures

Fig. 1
Fig. 1
General scheme for formation of Schiff bases.
Fig. 2
Fig. 2
The proposed structural formulae of metal complexes.
Fig. 3
Fig. 3
Suggested structure of Schiff base ligand and its metal(II) complexes where M = Cu(II), Ni(II) and Zn (II).
Fig. 4
Fig. 4
Schematic diagram for antibacterial activity and DNA interaction of the investigated complexes.
Fig. 5
Fig. 5
Proposed structure for the complexes.
Fig. 6
Fig. 6
Pt(II) complexes of reduced amino acid Schiff bases.
Fig. 7
Fig. 7
Structure of the Schiff base ligands H2L1–H2L4.
Fig. 8
Fig. 8
Mechanism of the catalytic reaction using investigated Mo complex.
Fig. 9
Fig. 9
Catalytic mechanism of catalyst CPS-[MoO2(ALGL)2] in epoxidation of cyclohexene to cyclohexene oxide by TBHP.
See this image and copyright information in PMC

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