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. 2020 Apr 10;21(7):2644.
doi: 10.3390/ijms21072644.

Novel Urethane-Dimethacrylate Monomers and Compositions for Use as Matrices in Dental Restorative Materials

Izabela M Barszczewska-Rybarek  1 , Marta W Chrószcz  1 , Grzegorz Chladek  2
Affiliations

Novel Urethane-Dimethacrylate Monomers and Compositions for Use as Matrices in Dental Restorative Materials

Izabela M Barszczewska-Rybarek et al. Int J Mol Sci. .

Abstract

In this study, novel urethane-dimethacrylate monomers were synthesized from 1,3-bis(1-isocyanato-1-methylethyl)benzene (MEBDI) and oligoethylene glycols monomethacrylates, containing one to three oxyethylene groups. They can potentially be utilized as matrices in dental restorative materials. The obtained monomers were used to prepare four new formulations. Two of them were solely composed of the MEBDI-based monomers. In a second pair, a monomer based on triethylene glycol monomethacrylate, used in 20 wt.%, was replaced with triethylene glycol dimethacrylate (TEGDMA), a reactive diluent typically used in dental materials. For comparison purposes, two formulations, using typical dental dimethacrylates (bisphenol A glycerolate dimethacrylate (Bis-GMA), urethane-dimethacrylate (UDMA) and TEGDMA) were prepared. The monomers and mixtures were tested for the viscosity and density. The homopolymers and copolymers, obtained via photopolymerization, were tested for the degree of conversion, polymerization shrinkage, water sorption and solubility, hardness, flexural strength and modulus. The newly developed formulations achieved promising physico-chemical and mechanical characteristics so as to be suitable for applications as dental composite matrices. A combination of the MEBDI-based urethane-dimethacrylates with TEGDMA resulted in copolymers with a high degree of conversion, low polymerization shrinkage, low water sorption and water solubility, and good mechanical properties. These parameters showed an improvement in relation to currently used dental formulations.

Keywords: degree of conversion; dental restorative materials; flexural properties; hardness; polymerization shrinkage; urethane-dimethacrylates; water sorption.

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Conflict of interest statement

The authors declare no conflict of interest. The funders had no role in the design of the study; in the collection, analyses, or interpretation of data; in the writing of the manuscript, or in the decision to publish the results.

Figures

Scheme 1
Scheme 1
The chemical structure of typical dental dimethacrylates.
Scheme 2
Scheme 2
The synthesis route and chemical structure of the MEBDI-based urethane-dimethacrylates synthesized in this study (HM – n = 1, DM – n = 2 and TM – n = 3).
Figure 1
Figure 1
The representative FTIR spectra of the DM: (a) monomer and (b) polymer.
Figure 2
Figure 2
Schematic representation of sample groups tested in this study.
See this image and copyright information in PMC

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