(2R,6R)-Hydroxynorketamine (HNK) plasma level predicts poor antidepressant response: is this the end of the HNK pipeline?
- PMID: 32291407
- PMCID: PMC7414015
- DOI: 10.1038/s41386-020-0668-1
(2R,6R)-Hydroxynorketamine (HNK) plasma level predicts poor antidepressant response: is this the end of the HNK pipeline?
Comment on
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Ketamine metabolites, clinical response, and gamma power in a randomized, placebo-controlled, crossover trial for treatment-resistant major depression.Neuropsychopharmacology. 2020 Jul;45(8):1398-1404. doi: 10.1038/s41386-020-0663-6. Epub 2020 Apr 6. Neuropsychopharmacology. 2020. PMID: 32252062 Free PMC article. Clinical Trial.
References
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- Farmer CR, Gilbert JR, Moaddel R, George J, Adeojo L, Lovett J, et al. Ketamine metabolites, clinical response, and gamma power in a randomized, placebo-controlled, crossover trial for treatment-resistant major depression. Neuropsychopharmacology. 2020 doi: 10.1038/s41386-020-0663-6. - DOI - PMC - PubMed
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