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. 2020 Jun 1;29(11):679-681.
doi: 10.1089/scd.2020.0071. Epub 2020 Apr 17.

Stem Cell-Based Therapy for Coronavirus Disease 2019

Robert Chunhua Zhao  1
Affiliations

Stem Cell-Based Therapy for Coronavirus Disease 2019

Robert Chunhua Zhao. Stem Cells Dev. .

Abstract

The novel coronavirus disease 2019 (COVID-19) has grown to be a global public-health emergency since patients were first detected in Wuhan, China, in December 2019. As of April 9, 2020, the novel coronavirus (named as SARS-CoV-2 by the International Committee on Taxonomy of Viruses on February 11) has infected 83,251 and 1,484,811 patients in China and the world, respectively. However, we have neither confirmed effective antiviral medications nor vaccines available to deal with this emergency. In this commentary, we offer an alternative promising therapy for COVID-19, that is, mesenchymal stem cell transplantation.

Keywords: COVID-19; clinical trial; transplantation.

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Conflict of interest statement

No competing financial interests exist.

References

    1. Huang C, Wang Y, Li X, Ren L, Zhao J, Hu Y, Zhang L, Fan G, Xu J, Gu X, Cheng Z, Yu T, Xia J, Wei Y, Wu W, Xie X, Yin W, Li H, Liu M, Xiao Y, Gao H, Guo L, Xie J, Wang G, Jiang R, Gao Z, Jin Q, Wang J and Cao B (2020). Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China. Lancet 395:497–506 - PMC - PubMed
    1. Guan WJ, Ni ZY, Hu Y, Liang WH, Ou CQ, He JX, Liu L, Shan H, Lei CL, Hui DSC, Du B, Li LJ, Zeng G, Yuen KY, Chen RC, Tang CL, Wang T, Chen PY, Xiang J, Li SY, Wang JL, Liang ZJ, Peng YX, Wei L, Liu Y, Hu YH, Peng P, Wang JM, Liu JY, Chen Z, Li G, Zheng ZJ, Qiu SQ, Luo J, Ye CJ, Zhu SY and Zhong NS (2020). Clinical characteristics of coronavirus disease 2019 in China. New Engl J Med [Epub ahead of print]; DOI: 10.1056/NEJMoa2002032. - DOI - PMC - PubMed
    1. Grasselli G, Zangrillo A, Zanella A, Antonelli M, Cabrini L, Castelli A, Cereda D, Coluccello A, Foti G, Fumagalli R, Iotti G, Latronico N, Lorini L, Merler S, Natalini G, Piatti A, Ranieri MV, Scandroglio AM, Storti E, Cecconi M, Pesenti and COVID-19 Lombardy A Network ICU (2020). Baseline characteristics and outcomes of 1591 patients infected with SARS-CoV-2 admitted to ICUs of the Lombardy region, Italy. JAMA [Epub ahead of print]; DOI: 10.1001/jama.2020.5394 - DOI - PMC - PubMed
    1. Young BE, Ong SWX, Kalimuddin S, Low JG, Tan SY, Loh J, Ng O-T, Marimuthu K, Ang LW, Mak TM, Lau SK, Anderson DE, Chan KS, Tan TY, Ng TY, Cui L, Said Z, Kurupatham L, Chen MI-C, Chan M, Vasoo S, Wang L-F, Tan BH, Lin RTP, Lee VJM, Leo Y-S, Lye and Singapore 2019 Novel Coronavirus Outbreak Research Team DC (2020). Epidemiologic features and clinical course of patients infected with SARS-CoV-2 in Singapore. JAMA [Epub ahead of print]; DOI: 10.1001/jama.2020.3204 - DOI - PMC - PubMed
    1. National Health Commission and National Administration of Traditional Chinese Medicine. (2020). Diagnosis and treatment protocol for novel coronavirus pneumonia (trial version 7). Chinese Med J 133:E027–E027 - PMC - PubMed

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