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Case Reports
. 2020 Jan-Mar;64(1):75-77.

Orbital metastatic neuroblastoma presenting as posttraumatic exophthalmos

Ana Maria Frunză  1 , Ovidiu Samoilă  2
Affiliations
Case Reports

Orbital metastatic neuroblastoma presenting as posttraumatic exophthalmos

Ana Maria Frunză et al. Rom J Ophthalmol. 2020 Jan-Mar.

Abstract

A 2-year-old female patient with a recent history of head trauma was admitted to the Ophthalmology Clinic with left exophthalmos. A differential diagnosis between traumatic and tumoral etiology was made. The orbitocranial MRI and fine needle ganglion biopsy settled the malignant etiology of the exophthalmia. Further investigations at the Pediatric Oncology Clinic decided on the diagnosis of orbital metastatic neuroblastoma. This case report presented an unusual association: orbital metastatic neuroblastoma becoming clinically positive soon after a head trauma.

Keywords: exophthalmia; neuroblastoma; orbit; trauma.

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Figures

Fig. 1
Fig. 1
MRI of the head showing a polypoid orbital tumoral mass with extension into the left frontal, temporal, sphenoid part, into the left temporal muscle and the left frontal conjunctive tissue
Fig. 2
Fig. 2
Fine needle aspiration biopsy, suggestive of a malignant tumor, small blue cells
See this image and copyright information in PMC

References

    1. Foster JA, Carter K, Durairaj V. 2017. Orbit, Eyelids, and Lacrimal System. In: Cantor L, Rapuano C, Cioffi G (eds.). Basic and Clinical Science Course, American Academy of Ophthalmology; p. 98.
    1. Smith V, Foster J. High-Risk Neuroblastoma Treatment Review. Children (Basel) 2018;5(9):114. - PMC - PubMed
    1. Heran Dreyfus F, Galatoire O, Koskas P, Lafitte F, Nau E, Bergès O. Orbito-palpebral vascular pathology. J Fr Ophtalmol. 2016;39(9):804–813. - PubMed
    1. Can SM, Aydin Y, Turkmenoglu O. Giant Cell Glioblastoma Manifesting as Traumatic Intracerebral Hemorrhage. Neurologia medico-chirurgica. 2002;42(12):568–571. - PubMed
    1. Usha RK, Vipul A, Akash DS, Urvashi S. Clinical features and management of posttraumatic subperiosteal hematoma of the orbit. Indian J Ophthalmol. 2011;59(1):55–58. - PMC - PubMed

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