Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1988;14(9):571-4.

A new antitumour agent, batracylin, selected by a preclinical solid tumour model

G Atassi  1 , P Dumont, H J Kabbe, O Yoder
Affiliations
  • PMID: 3229319

A new antitumour agent, batracylin, selected by a preclinical solid tumour model

G Atassi et al. Drugs Exp Clin Res. 1988.

Abstract

The antitumour efficacy of batracylin was investigated in vivo against murine tumours. The drug displayed an original spectrum of activity. It was totally inactive against L1210 leukaemia and B16 melanoma, while it was marginally active against ascitic P388 leukaemia. However, the tumour growth of the subcutaneously (s.c.) implanted colon 38 adenocarcinoma (Co 38) was completely inhibited in 80-90% of the mice. Therapeutic efficacy was retained upon oral administration and the drug was able to induce tumour regression in the advanced Co 38 disease. These data justify the selection of batracylin for toxicological studies and possible clinical investigations.

PubMed Disclaimer

Publication types

MeSH terms

LinkOut - more resources