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Editorial
. 2020 Apr 13;9(4):1104.
doi: 10.3390/jcm9041104.

Diagnostics, Risk Factors, Treatment and Outcomes of Acute Kidney Injury in a New Paradigm

Charat Thongprayoon  1 , Panupong Hansrivijit  2 , Karthik Kovvuru  3 , Swetha R Kanduri  3 , Aldo Torres-Ortiz  4 , Prakrati Acharya  5 , Maria L Gonzalez-Suarez  3 , Wisit Kaewput  6 , Tarun Bathini  7 , Wisit Cheungpasitporn  3
Affiliations
Editorial

Diagnostics, Risk Factors, Treatment and Outcomes of Acute Kidney Injury in a New Paradigm

Charat Thongprayoon et al. J Clin Med. .

Abstract

Acute kidney injury (AKI) is a common clinical condition among patients admitted in the hospitals. The condition is associated with both increased short-term and long-term mortality. With the development of a standardized definition for AKI and the acknowledgment of the impact of AKI on patient outcomes, there has been increased recognition of AKI. Two advances from past decades, the usage of computer decision support and the discovery of AKI biomarkers, have the ability to advance the diagnostic method to and further management of AKI. The increasingly widespread use of electronic health records across hospitals has substantially increased the amount of data available to investigators and has shown promise in advancing AKI research. In addition, progress in the finding and validation of different forms of biomarkers of AKI within diversified clinical environments and has provided information and insight on testing, etiology and further prognosis of AKI, leading to future of precision and personalized approach to AKI management. In this this article, we discussed the changing paradigms in AKI: from mechanisms to diagnostics, risk factors, and management of AKI.

Keywords: acute kidney injury; acute renal failure; biomarkers; critical care; predictors; renal replacement therapy; risk factors outcomes.

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Conflict of interest statement

We do not have any financial or non-financial potential conflicts of interest.

Figures

Figure 1
Figure 1
Baseline SCr, Adjust SCr for Fluid Balance, and Body Weights for Urine Output Criterion.
Figure 2
Figure 2
Causes of AKI.
Figure 3
Figure 3
Future of biomarkers of AKI. Abbreviations: GFR, glomerular filtration rate.
See this image and copyright information in PMC

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