Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2020 Feb 21;5(1):18.
doi: 10.1038/s41392-020-0127-9.

Potential benefits of precise corticosteroids therapy for severe 2019-nCoV pneumonia

Wei Zhou #  1 , Yisi Liu #  2 , Dongdong Tian #  3 , Cheng Wang #  4 , Sa Wang  5 , Jing Cheng  6 , Ming Hu  7 , Minghao Fang  8 , Yue Gao  9
Affiliations

Potential benefits of precise corticosteroids therapy for severe 2019-nCoV pneumonia

Wei Zhou et al. Signal Transduct Target Ther. .
No abstract available

PubMed Disclaimer

Conflict of interest statement

The authors declare no competing interests.

Figures

Fig. 1
Fig. 1
Corticosteroids treatment for severely ill patients with 2019-nCoV. a Demographics and baseline characteristics of patients infected with 2019-nCoV according to survival condition. aOf the 14 infections, 12 with identified pathogens, 2 diagnosed by characteristic clinical symptoms without identified pathogens; bN = 7. *P < 0.05, a significant difference between the two groups. b Part of indexes of 15 critically ill patients with 2019-nCoV infection during corticosteroids therapy. *P < 0.05 vs. the indexes on day 1. SaO2 oxygen saturation, CS corticosteroids, IMV invasive mechanical ventilation, PaO2/FiO2 ratio of arterial oxygen tension to fractional inspired oxygen concentrations, WBC white blood cell, CRP C-reaction protein, FIB fibrinogen
See this image and copyright information in PMC

References

    1. National Health Commission of the People’s Republic of China. National Health Commission’s briefing on the pneumonia epidemic situation released on 10 Feb 2020 (in Chinese). http://www.nhc.gov.cn/xcs/yqtb/202002/167a0e01b2d24274b03b2ca961107929.s... (2020).
    1. Wang W, Tang J, Wei F. Updated understanding of the outbreak of 2019 novel coronavirus (2019-nCoV) in Wuhan, China. J. Med. Virol. 2020 doi: 10.1002/jmv.25689. - DOI - PMC - PubMed
    1. National Health Commission of the People’s Republic of China. The 5th trial version of Diagnosis and Treatment Scheme for Pneumonitis with 2019-nCoV Infection (In Chinese). http://www.nhc.gov.cn/yzygj/s7653p/202002/d4b895337e19445f8d728fcaf1e3e1... (2020).
    1. Russell CD, Millar JE, Baillie JK. Clinical evidence does not support corticosteroid treatment for 2019-nCoV lung injury. Lancet. 2020 doi: 10.1016/s0140-6736(20)30317-2. - DOI - PMC - PubMed
    1. Jiang S, et al. Efficacy and safety of glucocorticoids in the treatment of severe community-acquired pneumonia: a meta-analysis. Medicine. 2019;98:e16239. doi: 10.1097/MD.0000000000016239. - DOI - PMC - PubMed

Publication types

MeSH terms