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Review
. 2020 Jun;99(6):1205-1208.
doi: 10.1007/s00277-020-04019-0. Epub 2020 Apr 15.

Mechanism of thrombocytopenia in COVID-19 patients

Panyang Xu  1 , Qi Zhou  2 , Jiancheng Xu  3
Affiliations
Review

Mechanism of thrombocytopenia in COVID-19 patients

Panyang Xu et al. Ann Hematol. 2020 Jun.

Abstract

Since December 2019, a novel coronavirus has spread throughout China and across the world, causing a continuous increase in confirmed cases within a short period of time. Some studies reported cases of thrombocytopenia, but hardly any studies mentioned how the virus causes thrombocytopenia. We propose several mechanisms by which coronavirus disease 2019 causes thrombocytopenia to better understand this disease and provide more clinical treatment options.

Keywords: Coronavirus disease 2019; Platelet; Severe acute respiratory syndrome coronavirus 2; Thrombocytopenia.

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Conflict of interest statement

The authors declare there they have no conflict of interest.

Figures

Fig. 1
Fig. 1
The possible mechanisms of thrombocytopenia in COVID-19 patients. SARS-CoV-2, severe acute respiratory syndrome coronavirus 2; COVID-19, coronavirus disease 2019; MK, megakaryocyte;↑, means an increase in a substance; ↓, means a decrease in a substance
See this image and copyright information in PMC

Comment in

  • Thrombocytopenia in COVID-19: pathophysiology matters.
    Gavriilaki E, Sakellari I, Gavriilaki M, Anagnostopoulos A. Gavriilaki E, et al. Ann Hematol. 2021 Aug;100(8):2139-2140. doi: 10.1007/s00277-020-04183-3. Epub 2020 Jul 18. Ann Hematol. 2021. PMID: 32683455 Free PMC article. No abstract available.

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