Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2020 Jun;17(3):161-170.
doi: 10.1007/s11904-020-00497-z.

PrEP Product Acceptability and Dual Process Decision-Making Among Men Who Have Sex with Men

Affiliations
Review

PrEP Product Acceptability and Dual Process Decision-Making Among Men Who Have Sex with Men

José A Bauermeister et al. Curr HIV/AIDS Rep. 2020 Jun.

Abstract

Purpose of review: Advances in short- and long-acting pre-exposure prophylaxis (PrEP) technologies have incentivized the need to understand how individuals make trade-offs and competing decisions regarding PrEP modalities. The purpose of this review was to examine how researchers have conceptualized and measured attributes that are either intuitive and emotional (System 1) or deliberative and cognitive (System 2) in conjoint analysis or discrete choice experiments focused on diverse PrEP technologies among men who have sex with men (MSM).

Recent findings: Across the 9 studies meeting inclusion criteria, 5 included oral PrEP, 3 included topical rectal microbicides, 4 included PrEP injectables, and 1 study focused on an HIV prevention vaccine. Studies have not used uniform metrics, making comparisons difficult. Researchers measured attributes linked to System 2 processing (e.g., cost, efficacy), yet none examined System 1 processing. There is not one product or attribute preferable to all groups. Prevention products will need to be developed and promoted to reflect that diversity. Given that PrEP technologies have been solely informed by System 2 attributes, efforts to integrate System 1 attributes into ongoing and future PrEP choice experiments are pivotal to advance PrEP acceptability research and interventions to support their implementation.

Keywords: Acceptability; Conjoint analysis; Decision-making; Discrete choice; Dual process.

PubMed Disclaimer

Conflict of interest statement

Conflicts of Interest

No potential conflicts of interest relevant to this article were reported.

References

    1. Beymer MR, Holloway IW, Pulsipher C, Landovitz RJ. Current and Future PrEP Medications and Modalities: On-demand, Injectables, and Topicals. Curr HIV/AIDS Rep. 2019;16(4):349–58. doi:10.1007/s11904-019-00450-9. - DOI - PMC - PubMed
    1. Nyaku AN, Kelly SG, Taiwo BO. Long-Acting Antiretrovirals: Where Are We now? Curr HIV/AIDS Rep. 2017;14(2):63–71. doi:10.1007/s11904-017-0353-0. - DOI - PubMed
    1. Kuehn B PrEP Disparities. JAMA. 2018;320(22):2304. doi:10.1001/jama.2018.18947. - DOI - PubMed
    1. Siegler AJ, Bratcher A, Weiss KM, Mouhanna F, Ahlschlager L, Sullivan PS. Location location location: an exploration of disparities in access to publicly listed pre-exposure prophylaxis clinics in the United States. Ann Epidemiol. 2018;28(12):858–64. doi:10.1016/j.annepidem.2018.05.006. - DOI - PMC - PubMed
    1. Calabrese SK, Krakower DS, Mayer KH. Integrating HIV Preexposure Prophylaxis (PrEP) Into Routine Preventive Health Care to Avoid Exacerbating Disparities. Am J Public Health. 2017;107(12):1883–9. doi:10.2105/AJPH.2017.304061. - DOI - PMC - PubMed

Publication types

MeSH terms

Substances