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. 1988 Dec;26(12):2561-3.
doi: 10.1128/jcm.26.12.2561-2563.1988.

Calculation of antibody affinity in homogeneous and heterogeneous systems

R R Chalquest  1
Affiliations

Calculation of antibody affinity in homogeneous and heterogeneous systems

R R Chalquest. J Clin Microbiol. 1988 Dec.

Abstract

Antibody affinity is an important determinant of all antibody-antigen reactions. A new computer program, AFCRV, was developed to calculate binding constants with data from a radioimmunoassay on most microcomputers in the laboratory by using constant-ratio dilution curves. Evaluation of a homogeneous or heterogeneous antibody in the presence of a single antigen can be accomplished.

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