Protein Aggregation Triggered by Rewired Protein Homeostasis during Neuronal Differentiation
- PMID: 32302540
- DOI: 10.1016/j.molcel.2020.03.028
Protein Aggregation Triggered by Rewired Protein Homeostasis during Neuronal Differentiation
Abstract
In this issue of Molecular Cell, Vonk et al. (2020) and Thiruvalluvan et al. (2020) identify key chaperones that confer resistance to protein aggregation in neural stem cells and become reduced upon differentiation.
Copyright © 2020. Published by Elsevier Inc.
Comment on
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Differentiation Drives Widespread Rewiring of the Neural Stem Cell Chaperone Network.Mol Cell. 2020 Apr 16;78(2):329-345.e9. doi: 10.1016/j.molcel.2020.03.009. Epub 2020 Apr 7. Mol Cell. 2020. PMID: 32268122 Free PMC article.
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DNAJB6, a Key Factor in Neuronal Sensitivity to Amyloidogenesis.Mol Cell. 2020 Apr 16;78(2):346-358.e9. doi: 10.1016/j.molcel.2020.02.022. Epub 2020 Apr 7. Mol Cell. 2020. PMID: 32268123
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