The Role of Nutrition in Attenuating Age-Related Skeletal Muscle Atrophy
- PMID: 32304039
- DOI: 10.1007/978-3-030-42667-5_12
The Role of Nutrition in Attenuating Age-Related Skeletal Muscle Atrophy
Abstract
The elderly population is increasing rapidly worldwide, and we are faced with the significant challenge for maintaining or improving physical activity, independence, and quality of life. Sarcopenia, the age-related decline of skeletal muscle mass, is characterized by loss of muscle quantity and quality resulting to a gradual slowing of movement, a decrease in strength and power, elevated risk of fall-related injury, and often frailty. Supplemental, hormonal, and pharmacological approaches have been attempted to attenuate sarcopenia but these have not achieved outstanding results. In this review, we summarize the current knowledge of nutrition-based therapies for counteracting sarcopenia.
Keywords: Aging; Diet; Exercise; Muscle atrophy; Nutrition; Sarcopenia.
Similar articles
-
Molecular mechanisms in aging and current strategies to counteract sarcopenia.Curr Aging Sci. 2010 Jul;3(2):90-101. doi: 10.2174/1874609811003020090. Curr Aging Sci. 2010. PMID: 20158492 Review.
-
Assistive technologies to overcome sarcopenia in ageing.Maturitas. 2018 Jun;112:78-84. doi: 10.1016/j.maturitas.2018.04.003. Epub 2018 Apr 10. Maturitas. 2018. PMID: 29704921 Review.
-
Age-related changes in skeletal muscle: changes to life-style as a therapy.Biogerontology. 2018 Dec;19(6):519-536. doi: 10.1007/s10522-018-9775-3. Epub 2018 Sep 27. Biogerontology. 2018. PMID: 30259289 Free PMC article. Review.
-
Recent advances in pharmacological, hormonal, and nutritional intervention for sarcopenia.Pflugers Arch. 2018 Mar;470(3):449-460. doi: 10.1007/s00424-017-2077-9. Epub 2017 Oct 18. Pflugers Arch. 2018. PMID: 29043432 Review.
-
Protein and exercise in the prevention of sarcopenia and aging.Nutr Res. 2017 Apr;40:1-20. doi: 10.1016/j.nutres.2017.01.001. Epub 2017 Jan 16. Nutr Res. 2017. PMID: 28473056 Review.
Cited by
-
Eicosapentaenoic acid and branched-chain amino acids fortified complete nutrition drink improved muscle strength in older individuals with inadequate protein intake.Front Nutr. 2023 Jun 30;10:1164469. doi: 10.3389/fnut.2023.1164469. eCollection 2023. Front Nutr. 2023. PMID: 37457975 Free PMC article.
-
Molecular Mechanisms Underlying Intensive Care Unit-Acquired Weakness and Sarcopenia.Int J Mol Sci. 2022 Jul 29;23(15):8396. doi: 10.3390/ijms23158396. Int J Mol Sci. 2022. PMID: 35955530 Free PMC article. Review.
-
Integrative metagenomics and metabolomics reveal age-associated gut microbiota and metabolite alterations in a hamster model of COVID-19.Gut Microbes. 2025 Dec;17(1):2486511. doi: 10.1080/19490976.2025.2486511. Epub 2025 Apr 2. Gut Microbes. 2025. PMID: 40172215 Free PMC article.
-
Supplementation with Bioactive Compounds Improves Health and Rejuvenates Biological Age in Postmenopausal Women.Biomolecules. 2025 May 20;15(5):739. doi: 10.3390/biom15050739. Biomolecules. 2025. PMID: 40427632 Free PMC article.
-
Sarcopenia: Molecular Pathways and Potential Targets for Intervention.Int J Mol Sci. 2020 Nov 22;21(22):8844. doi: 10.3390/ijms21228844. Int J Mol Sci. 2020. PMID: 33266508 Free PMC article. Review.
Publication types
MeSH terms
LinkOut - more resources
Full Text Sources
Medical