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. 2020 Jun;8(6):539-541.
doi: 10.1016/S2213-2600(20)30172-7. Epub 2020 Apr 15.

Hydroxychloroquine in the management of critically ill patients with COVID-19: the need for an evidence base

Affiliations

Hydroxychloroquine in the management of critically ill patients with COVID-19: the need for an evidence base

Fabio S Taccone et al. Lancet Respir Med. 2020 Jun.
No abstract available

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References

    1. Yang X, Yu Y, Xu J. Clinical course and outcomes of critically ill patients with SARS-CoV-2 pneumonia in Wuhan, China: a single-centered, retrospective, observational study. Lancet Respir Med. 2020 doi: 10.1016/S2213-2600(20)30079-5. published online Feb 24. - DOI - PMC - PubMed
    1. Simonis FD, Serpa NA, Binnekade JM. Effect of a low vs intermediate tidal volume strategy on ventilator-free days in intensive care unit patients without ARDS: a randomized clinical trial. JAMA. 2018;320:1872–1880. - PMC - PubMed
    1. Yao X, Ye F, Zhang M. In vitro antiviral activity and projection of optimized dosing design of hydroxychloroquine for the treatment of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Clin Infect Dis. 2020 doi: 10.1093/cid/ciaa237. published online March 9. - DOI - PMC - PubMed
    1. Liu J, Cao R, Xu M. Hydroxychloroquine, a less toxic derivative of chloroquine, is effective in inhibiting SARS-CoV-2 infection in vitro. Cell Discov. 2020;6:16. - PMC - PubMed
    1. Wang M, Cao R, Zhang L. Remdesivir and chloroquine effectively inhibit the recently emerged novel coronavirus (2019-nCoV) in vitro. Cell Res. 2020;30:269–271. - PMC - PubMed

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