Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2021 Jul 15;15(4):492-499.
doi: 10.5009/gnl20031.

Current Status of Mucosal Imaging with Narrow-Band Imaging in the Esophagus

Keng Hoong Chiam  1 , Seon Ho Shin  1 , Kun Cheong Choi  1 , Florencia Leiria  1 , Mariana Militz  1 , Rajvinder Singh  1   2
Affiliations
Review

Current Status of Mucosal Imaging with Narrow-Band Imaging in the Esophagus

Keng Hoong Chiam et al. Gut Liver. .

Abstract

Recent advances in endoscopic imaging of the esophagus have revolutionized the diagnostic capability for detecting premalignant changes and early esophageal malignancy. In this article, we review the practical application of narrow-band imaging focusing on diseases of the esophagus, including Barrett's esophagus, adenocarcinoma, and squamous cell carcinoma.

Keywords: Barrett's esophagus; Esophageal adenocarcinoma; Esophageal squamous cell carcinoma; Mucosal imaging; Narrow band imaging.

PubMed Disclaimer

Conflict of interest statement

CONFLICTS OF INTEREST

No potential conflict of interest relevant to this article was reported.

Figures

Fig. 1
Fig. 1
Round pits and regular microvasculature (no dysplasia).
Fig. 2
Fig. 2
Ridged/villous pits and regular microvasculature (no dysplasia).
Fig. 3
Fig. 3
Absent pits and regular microvasculature (no dysplasia).
Fig. 4
Fig. 4
Irregular/absent pits and irregular microvasculature (high-grade dysplasia).
Fig. 5
Fig. 5
Dilated vasculature but no change in caliber (equivocal).
Fig. 6
Fig. 6
Diagram showing invasion depth according to different types of intrapapillary capillary loop patterns. EP, epithelium; LP, lamina propria; MM, muscularis mucosa; SM, submucosa; MP, muscularis propria.
Fig. 7
Fig. 7
Type A microvessels without severe irregularity—these findings are indicative of normal, inflammatory or low-grade intraepithelial neoplasia.
Fig. 8
Fig. 8
Type B1 microvessels with severe irregularity but with a closed loop formation—these findings are consistent with high-grade intraepithelial neoplasia or squamous cell carcinoma limited to the lamina propria.
Fig. 9
Fig. 9
Type B2 microvessels with severe irregularity without a loop-like formation indicative of invasive cancer beyond but limited to less than 200 µm of the submucosa.
See this image and copyright information in PMC

References

    1. Banerjee R, Reddy N. A primer on narrow band imaging. Paras Publishing; Hyderabad: 2009.
    1. Mangira D, Wong S, Sharma P, Singh R. Virtual chromoendoscopy. In: Konda VJA, Waxman I, editors. Endoscopic imaging techniques and tools. 1st ed. Springer; Basel: 2016. pp. 49–60. - DOI
    1. Kuznetsov K, Lambert R, Rey JF. Narrow-band imaging: potential and limitations. Endoscopy. 2006;38:76–81. doi: 10.1055/s-2005-921114. - DOI - PubMed
    1. Gono K, Obi T, Yamaguchi M, et al. Appearance of enhanced tissue features in narrow-band endoscopic imaging. J Biomed Opt. 2004;9:568–577. doi: 10.1117/1.1695563. - DOI - PubMed
    1. Kara MA, Ennahachi M, Fockens P, ten Kate FJ, Bergman JJ. Detection and classification of the mucosal and vascular patterns (mucosal morphology) in Barrett's esophagus by using narrow band imaging. Gastrointest Endosc. 2006;64:155–166. doi: 10.1016/j.gie.2005.11.049. - DOI - PubMed

LinkOut - more resources