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. 2020 May;30(5):686-691.
doi: 10.1017/S1047951120000785. Epub 2020 Apr 20.

Fetal CHD and perinatal outcomes

Christina J Ge  1 , Amanda C Mahle  2 , Irina Burd  2 , Eric B Jelin  3 , Priya Sekar #  4 , Angie C Jelin #  2
Affiliations

Fetal CHD and perinatal outcomes

Christina J Ge et al. Cardiol Young. 2020 May.

Abstract

Objective: To evaluate delivery management and outcomes in fetuses prenatally diagnosed with CHD.

Study design: A retrospective cohort study was conducted on 6194 fetuses (born between 2013 and 2016), comparing prenatally diagnosed with CHD (170) to those with non-cardiac (234) and no anomalies (5790). Primary outcomes included the incidence of preterm delivery and mode of delivery.

Results: Gestational age at delivery was significantly lower between the CHD and non-anomalous cohorts (38.6 and 39.1 weeks, respectively). Neonates with CHD had a significantly lower birth weights (p < 0.001). There was an approximately 1.5-fold increase in the rate of primary cesarean sections associated with prenatally diagnosed CHD with an odds ratio of 1.49 (95% CI 1.06-2.10).

Conclusions: Our study provides additional evidence that the prenatal diagnosis of CHD is associated with a lower birth weight, preterm delivery, and with an increased risk of delivery by primary cesarean section.

Keywords: CHD; fetal anomalies; prenatal; preterm delivery; ultrasound.

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Conflict of interest statement

Conflicts of interest. None.

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