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. 2020 Apr 9:16:943-948.
doi: 10.2147/NDT.S245857. eCollection 2020.

Prediction of Risk Factors for the Evolution of Traumatic Subdural Effusion into Chronic Subdural Hematoma

Sansong Chen  1 , Hui Peng  2 , Xuefei Shao  1 , Lin Yao  1 , Jie Liu  1 , Jiongping Tian  1 , Lean Sun  1 , Yi Dai  1 , Xiaochun Jiang #  1 , Limin Cheng #  3
Affiliations

Prediction of Risk Factors for the Evolution of Traumatic Subdural Effusion into Chronic Subdural Hematoma

Sansong Chen et al. Neuropsychiatr Dis Treat. .

Abstract

Purpose: To explore the risk factors of the evolution of traumatic subdural effusion (TSE) into chronic subdural hematoma (CSDH).

Materials and methods: The 70 patients' gender, age, location of effusion, unilateral and bilateral, Glasgow coma score (GCS) at admission, presence or absence of brain contusion, the time of effusion appeared, daily amount of mannitol, mannitol number of days used, with or without atorvastatin calcium tablets, with or without antiplatelet aggregation drugs, with or without anticoagulant drugs, with or without abnormalities in blood coagulation routines, computed tomography (CT) layer height, the thickness, and CT value of the first effusion were analyzed by single factor. Logistic multivariate regression analysis was performed on the statistically significant indicators. Power of the regression model was evaluated using receiver operating characteristic (ROC) curve.

Results: Univariate analysis showed that the presence or absence of brain contusion, the time of effusion appeared, atorvastatin calcium tablets use or not, the CT value of the effusion, and TSE into CSDH evolution varied significantly compared to the non-evolved group (P<0.05). Logistic multivariate regression analysis showed that combined brain contusion (odds ratio (OR)=16.247, 95% confidence interval (CI), 1.831-144.157, P = 0.012), early onset of effusion (OR = 0.573, 95% CI: 0.349-0.941, P = 0.028), atorvastatin calcium tablets not used after effusion (OR = 60.028, 95% CI: 6.103-590.399, P = 0.0001), and high CT value (OR = 1.285, 95% CI: 1.067-1.547, P = 0.008) were risk factors for the evolution of TSE into CSDH. The ROC model suggested that the prediction of these risk factors had high diagnostic accuracy.

Conclusion: TSE patients with brain contusion, early onset of effusion, without the usage of atorvastatin calcium tablets after effusion, and high CT value of the first effusion are at a risk of evolving into CSDH.

Keywords: CSDH; TSE; evolution; risk factors.

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Conflict of interest statement

The authors do not have any actual or potential conflicts of interest with other people or organizations.

Figures

Figure 1
Figure 1
Receiver operating characteristic curve of the independent risk factors obtained from the multivariate logistic regression analysis. (A) combined brain contusion (AUC = 0.694, P = 0.017), no consumption of atorvastatin calcium (AUC = 0.777, P = 0.001), high CT value of effusion (AUC = 0.720, P = 0.007). (B) the time of the effusion appearance (AUC = 0.735, P = 0.004).
See this image and copyright information in PMC

References

    1. Xu F. The research progress of traumatic subdural effusion. Int J Neurol Neurosurg. 2011;38:182–185.
    1. John JN, Dila C. Traumatic subdural hydroma in adults. Neurosurgery. 1981;9:621–625. - PubMed
    1. Liu YG, Jia T, Liu M. Typing and clinical characteristics of traumatic subdural effusion. Chi J Surg. 2003;41(10):763–765. - PubMed
    1. Liu YG, Zhu SG, Jiang YQ. Evolution of traumatic subdural hydroma into chronic subdural hematoma. Chi J Surg. 2002;40(5):360–362. - PubMed
    1. Cao DM, Qi WT, Wu YK. Atorvastatin clinical study on reducing the conversion of traumatic subdural effusion into chronic subdural hematoma. Chi J Crit Care Med (Electronic Edition). 2018;11(3):197–199.