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. 2020 Mar 4:2019:380-388.
eCollection 2019.

Enabling Privacy Preserving Record Linkage Systems Using Asymmetric Key Cryptography

Affiliations

Enabling Privacy Preserving Record Linkage Systems Using Asymmetric Key Cryptography

Xiao Dong et al. AMIA Annu Symp Proc. .

Abstract

We present a systemic approach to devise and deploy Privacy Preserving Record Linkage (PPRL) systems using asymmetric key cryptography and illustrate the strengths of such an approach. With our approach, the security implications of sharing a common secret salt across the network may be avoided, allowing the local participating sites to use private keys along with the current cryptographic hashes to maximally secure their own data. In addition, the final cyphertext tokens are compatible with those used by existing record linkage modules, allowing seamless integration with the existing PPRL infrastructures for downstream analysis. Finally, study-specific hash production requires action only by the central party. The main intuition for this work is derived from how asymmetric key approaches have enabled internet-scale applications. We demonstrate that such a design, where the local sites no longer need special-purpose software, affords greater flexibility and scalability for large scale multi-site linkage studies.

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Figures

Figure 1.
Figure 1.
Key generation and hash signature generation workflow.
Figure 2.
Figure 2.
Pseudo-hash generation workflow.

References

    1. Jiang X, Sarwate AD, Ohno-Machado L. Privacy Technology to Support Data Sharing for Comparative Effectiveness Research. A Systematic Review. 2013;51(8 SUPPL.3) Med Care. - PMC - PubMed
    1. Schnell R, Bachteler T, Reiher J. Privacy-preserving Record Linkage Using Bloom Filters. BMC Med Inform Decis Mak. 2009;9(1) - PMC - PubMed
    1. Chen F, Jiang X, Wang S, et al. Perfectly Secure and Efficient Two-party Electronic-health-record Linkage. IEEE Internet Comput. 2018;22(2):32–41. - PMC - PubMed
    1. Ong T, Lazrig I, Ray I, Ray I, Kahn M. Scalable Secure Privacy-preserving Record Linkage (PPRL) Methods Using Cloud-based Infrastructure. Int J Popul Data Sci. 2018;3(4)
    1. Dang QH. Secure Hash Standard. Fed Inf Process Stand Publ. 2015:180–4.

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