A quickly, effectively screening process of novel corona virus disease 2019 (COVID-19) in children in Shanghai, China

Yu Shi¹, Xiangshi Wang², Gongbao Liu¹, Qirong Zhu², Jianshe Wang², Hui Yu², Chuanqing Wang³, Libo Wang⁴, Mingzhi Zhang⁴, Lingen Zhang⁵, Guoping Lu⁵, Zhujin Lu⁵, Jian Yu⁶, Zhongwei Qiao⁷, Ying Gu⁸, Guomei Shen⁹, Hong Xu^{10

11}, Mei Zeng², Xiaowen Zhai^{11

12}, Guoying Huang^{11

13}

Affiliations

¹ Division of Medical Administration, National Children's Medical Center, Children's Hospital of Fudan University, Shanghai 201102, China.
² Department of Infectious Disease, National Children's Medical Center, Children's Hospital of Fudan University, Shanghai 201102, China.
³ Department of Hospital Infection Control, National Children's Medical Center, Children's Hospital of Fudan University, Shanghai 201102, China.
⁴ Department of Respiration, National Children's Medical Center, Children's Hospital of Fudan University, Shanghai 201102, China.
⁵ Department of Critical Care Medicine, National Children's Medical Center, Children's Hospital of Fudan University, Shanghai 201102, China.
⁶ Department of Traditional Chinese Medicine, National Children's Medical Center, Children's Hospital of Fudan University, Shanghai 201102, China.
⁷ Department of Medical Image, National Children's Medical Center, Children's Hospital of Fudan University, Shanghai 201102, China.
⁸ Department of Nursing, National Children's Medical Center, Children's Hospital of Fudan University, Shanghai 201102, China.
⁹ Outpatient and Emergency Management Office, National Children's Medical Center, Children's Hospital of Fudan University, Shanghai 201102, China.
¹⁰ Department of Nephrology/Rheumatology, National Children's Medical Center, Children's Hospital of Fudan University, Shanghai 201102, China.
¹¹ Hospital Administration, National Children's Medical Center, Children's Hospital of Fudan University, Shanghai 201102, China.
¹² Department of Hematology/Oncology, National Children's Medical Center, Children's Hospital of Fudan University, Shanghai 201102, China.
¹³ Heart Center, National Children's Medical Center, Children's Hospital of Fudan University, Shanghai 201102, China.

PMID: 32309388
PMCID: PMC7154461
DOI: 10.21037/atm.2020.03.22

A quickly, effectively screening process of novel corona virus disease 2019 (COVID-19) in children in Shanghai, China

Yu Shi et al. Ann Transl Med. 2020 Mar.

. 2020 Mar;8(5):241.

doi: 10.21037/atm.2020.03.22.

Authors

Affiliations

¹ Division of Medical Administration, National Children's Medical Center, Children's Hospital of Fudan University, Shanghai 201102, China.
² Department of Infectious Disease, National Children's Medical Center, Children's Hospital of Fudan University, Shanghai 201102, China.
³ Department of Hospital Infection Control, National Children's Medical Center, Children's Hospital of Fudan University, Shanghai 201102, China.
⁴ Department of Respiration, National Children's Medical Center, Children's Hospital of Fudan University, Shanghai 201102, China.
⁵ Department of Critical Care Medicine, National Children's Medical Center, Children's Hospital of Fudan University, Shanghai 201102, China.
⁶ Department of Traditional Chinese Medicine, National Children's Medical Center, Children's Hospital of Fudan University, Shanghai 201102, China.
⁷ Department of Medical Image, National Children's Medical Center, Children's Hospital of Fudan University, Shanghai 201102, China.
⁸ Department of Nursing, National Children's Medical Center, Children's Hospital of Fudan University, Shanghai 201102, China.
⁹ Outpatient and Emergency Management Office, National Children's Medical Center, Children's Hospital of Fudan University, Shanghai 201102, China.
¹⁰ Department of Nephrology/Rheumatology, National Children's Medical Center, Children's Hospital of Fudan University, Shanghai 201102, China.
¹¹ Hospital Administration, National Children's Medical Center, Children's Hospital of Fudan University, Shanghai 201102, China.
¹² Department of Hematology/Oncology, National Children's Medical Center, Children's Hospital of Fudan University, Shanghai 201102, China.
¹³ Heart Center, National Children's Medical Center, Children's Hospital of Fudan University, Shanghai 201102, China.

PMID: 32309388
PMCID: PMC7154461
DOI: 10.21037/atm.2020.03.22

Abstract

Background: A recent cluster of pneumonia cases in China was caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). We report the screening and diagnosis of corona virus disease 2019 (COVID-19) in our hospital.

Methods: Developed a procedure for the identification of children cases with COVID-19 in outpatient and emergency department of our hospital, then we observed how this process works.

Results: (I) There were 56 cases considered suspected cases, and 10 cases were confirmed as COVID-19. (II) Of the 10 confirmed COVID-19 cases admitted in our hospital, 5 were males and 5 were females, aged from 7 months to 11 years, the average age is 6.0±4.2 years, 6 cases were mild pneumonia, the others were upper respiratory tract infection. (III) We followed up 68 patients in isolation at home until symptoms disappeared. Non were missed in the patient's first visit. The sensitivity of this method is 100% and the specificity is 71.3%.

Conclusions: Our screening process works well, and it is also necessary to establish a screening network in the hospital.

Keywords: Corona virus disease 2019 (COVID-19); child; diagnosis; severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

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Conflict of interest statement

Conflicts of Interest: The authors have no conflicts of interest to declare.

Figures

**Figure 1**
Outpatient and emergency procedures for suspected patients. A case considered as an observation case or a suspected case is determined by the MDT director, infection-control. MDT, multidisciplinary team.

**Figure 2**
Rapid screening algorithm for COVID-19 cases suspected and confirmed in children.

See this image and copyright information in PMC

References

1. Eurosurveillance Editorial Team. Note from the editors: novel coronavirus (2019-nCoV). Euro Surveill 2020. doi: 10.2807/1560-7917.ES.2020.25.3.2001231. - DOI
1. Zhu N, Zhang D, Wang W, et al. A Novel Coronavirus from Patients with Pneumonia in China, 2019. N Engl J Med 2020;382:727-33. 10.1056/NEJMoa2001017 - DOI - PMC - PubMed
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A quickly, effectively screening process of novel corona virus disease 2019 (COVID-19) in children in Shanghai, China

Affiliations

A quickly, effectively screening process of novel corona virus disease 2019 (COVID-19) in children in Shanghai, China

Authors

Affiliations

Abstract

Conflict of interest statement

Figures

References

LinkOut - more resources

Full Text Sources

Miscellaneous