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Case Reports
. 2020 Jan 7;7(1):e00299.
doi: 10.14309/crj.0000000000000299. eCollection 2020 Jan.

Pancreatic Adenocarcinoma With Synchronous Colonic Metastases

Rohan Yewale  1 , Banumathi Ramakrishna  2 , Kavita Vijaykumar  2 , Partheeban Balasundaram  2 , S Arulprakash  1 , Patta Radhakrishna  3 , B S Ramakrishna  1
Affiliations
Case Reports

Pancreatic Adenocarcinoma With Synchronous Colonic Metastases

Rohan Yewale et al. ACG Case Rep J. .

Abstract

Metastases from pancreatic malignancy are commonly known to occur in the regional lymph nodes, liver, lung, and peritoneum. Synchronous or metachronous metastasis from the pancreas to the colon is rare, with only 6 cases reported in the literature. We report a man who was found to have adenocarcinoma on biopsies from synchronous lesions in the colon and the pancreas. The immunohistochemistry report revealed the diagnosis of a primary pancreatic malignancy with synchronous colonic metastases.

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Figures

Figure 1.
Figure 1.
Colonoscopy showing focal scarring and puckering of mucosa in the descending and sigmoid colon mimicking the appearance of healed ulcers.
Figure 2.
Figure 2.
Colonic biopsy. Neoplastic glands (A) showing diffuse strong positive staining for CK7 and (B) are predominantly negative with only a few tumor cells showing positive staining for CK20 (40×).
Figure 3.
Figure 3.
Fine-needle aspiration biopsy of the pancreas. Neoplastic glands showing (A) diffuse strong positive staining for CK7 and (B) focal positive staining in a few tumor cells for CK20 (400×).
See this image and copyright information in PMC

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