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Editorial
. 2020 Feb 26;4(2):e355.
doi: 10.1097/HS9.0000000000000355. eCollection 2020 Apr.

High Five for Low Five

Affiliations
Editorial

High Five for Low Five

Roger E G Schutgens. Hemasphere. .
No abstract available

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Conflict of interest statement

The authors have no conflicts of interest to disclose.

Figures

Figure 1
Figure 1
Schematic representation of the coagulation cascade. Factor V, factor VIII and factor X are indicated in color to highlight the possible competition between factor V and factor VIII for factor Xa. TF = tissue factor.

References

    1. Ellery PER, Hilden I, Thyregod P, et al. Measurement of plasma and platelet tissue factor pathway inhibitor, factor V and Protein S in people with haemophilia. Haemophilia. 2019;25:1083–1091. - PMC - PubMed
    1. Link KG, Stobb MT, Sorrells MG, et al. A mathematical model of coagulation under flow identifies factor V as a modifier of thrombin generation in hemophilia A. J Thromb Haemost. 2020;18:306–317. - PMC - PubMed
    1. Shao Y, Wu W, Xu G, et al. Low factor V level ameliorates bleeding diathesis in patients with combined deficiency of factor V and factor VIII. Blood. 2019;134:1745–1754. - PubMed

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