Multidrug-Resistant Salmonella Serotype Anatum in Travelers and Seafood from Asia, United States

Abstract

A multidrug-resistant Salmonella enterica serotype Anatum strain reported in Taiwan was isolated in the United States from patients and from seafood imported from Asia. Isolates harbored 11 resistance determinants, including quinolone and inducible cephalosporin resistance genes. Most patients had traveled to Asia. These findings underscore the need for global One Health resistance surveillance.

Keywords: Anatum; Asia; DHA-1; MDR; Salmonella; Salmonella enterica serotype Anatum; United States; antimicrobial resistance; bacteria; beta-lactamases; blaDHA-1; food safety; foodborne diseases; imported; seafood; shrimp; tilapia; travel.

Figure

Core genome multilocus sequence typing (cgMLST) phylogenetic tree of 40 Salmonella enterica serotype Anatum isolates, 2015–2019. The tree was constructed by using BioNumerics version 7.6 (Applied Maths, http://www.applied-maths.com). Isolate sources, collection years, and National Center for Biotechnology Information strain or isolate numbers are shown. For isolates from the United States, international travel destinations of patients and sources of imported foods are provided. Dark gray boxes indicate resistance determinants detected: 1) aadA2; 2) aph(3″)-Ib (strA); 3) aph (6)-Id (strB); 4) bla_DHA-1; 5) dfrA23; 6) floR; 7) lnu(F); 8) qnrB4; 9) sul1; 10) sul2; 11) tet(A); 12) aadA1; 13) bla_TEM-1B; 14) dfrA1; 15) dfrA12; 16) mcr-1.1; 17) mph(A); 18) oqxAB; 19) qnrA6; 20) sul3. Scale bar indicates percentage similarity. JAP, Japan; MX, Mexico; NA, not available; PHL, Philippines; TWN, Taiwan; UK, United Kingdom; USA, United States.