Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2020 May;26(5):1047-1049.
doi: 10.3201/eid2605.200116.

Human Adenovirus 7d Strains Associated with Influenza-Like Illness, New York, USA, 2017-2019

Human Adenovirus 7d Strains Associated with Influenza-Like Illness, New York, USA, 2017-2019

Daryl M Lamson et al. Emerg Infect Dis. 2020 May.

Abstract

Human adenovirus 7d is a respiratory pathogen capable of causing acute respiratory disease of variable severity. Phylogenetic analysis of whole-genome sequences of 15 strains isolated from cases of influenza-like-illness during 2017-2019 demonstrated the circulation of 2 distinct clades of genomic variant 7d in colleges in New York, USA.

Keywords: Human adenovirus 7; New York; United States; colleges; genetic diversity; influenza-like illness; phylogenetic analysis; viruses; whole-genome sequence.

PubMed Disclaimer

Figures

Figure
Figure
Maximum-likelihood tree showing the phylogenetic relationships of human adenovirus genome type 7d isolates from New York, USA (bold), and reference sequences obtained from GenBank. Accession numbers for reference strains are provided next to the strain designation, country, and year of isolation. Strain USA IL/NHRC1315/1997 of genomic variant 7d2 was included in the analysis as a representative of genome types circulating in the United States before 2013. Nodes with bootstrap values >70 are displayed. Scale bar indicates nucleotide substitutions per site.

References

    1. Scott MK, Chommanard C, Lu X, Appelgate D, Grenz L, Schneider E, et al. Human adenovirus associated with severe respiratory infection, Oregon, USA, 2013–2014. Emerg Infect Dis. 2016;22:1044–51. 10.3201/eid2206.151898 - DOI - PMC - PubMed
    1. Kajon AE, Ison MG. Severe infections with human adenovirus 7d in 2 adults in family, Illinois, USA, 2014. Emerg Infect Dis. 2016;22:730–3. 10.3201/eid2204.151403 - DOI - PMC - PubMed
    1. Zhao S, Wan C, Ke C, Seto J, Dehghan S, Zou L, et al. Re-emergent human adenovirus genome type 7d caused an acute respiratory disease outbreak in Southern China after a twenty-one year absence. Sci Rep. 2014;4:7365. 10.1038/srep07365 - DOI - PMC - PubMed
    1. Killerby ME, Rozwadowski F, Lu X, Caulcrick-Grimes M, McHugh L, Haldeman AM, et al. Respiratory illness associated with emergent human adenovirus genome type 7d, New Jersey, 2016–2017. Open Forum Infect Dis. 2019;6:ofz017. 10.1093/ofid/ofz017 - DOI - PMC - PubMed
    1. Bautista-Gogel J, Madsen CM, Lu X, Sakthivel SK, Froh I, Kamau E, et al. Outbreak of respiratory illness associated with human adenovirus type 7 among persons attending Officer Candidates School, Quantico, Virginia, 2017. J Infect Dis. 2019. 10.1093/infdis/jiz060 - DOI - PubMed

Publication types