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Book

Streptomycin

Mitchell Waters  1 , Prasanna Tadi  2
In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2025 Jan.
.
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Free Books & Documents
Book

Streptomycin

Mitchell Waters et al.
Free Books & Documents

Excerpt

Streptomycin is the first discovered aminoglycoside antibiotic, originally isolated from the bacteria Streptomyces griseus. It is now primarily used as part of the multi-drug treatment of pulmonary tuberculosis. It has additional activity against several aerobic gram-negative bacteria. This activity will discuss the indications, mechanism of action, and contraindications of using streptomycin in both children and adults. It will also describe the administration, dosing, and monitoring of streptomycin. Additionally, it will touch on the adverse event profile and other key factors to keep in mind as a healthcare team when using streptomycin as an antibiotic agent to treat pulmonary tuberculosis or other aerobic gram-negative infections.

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Conflict of interest statement

Disclosure: Mitchell Waters declares no relevant financial relationships with ineligible companies.

Disclosure: Prasanna Tadi declares no relevant financial relationships with ineligible companies.

References

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    1. Camba SA, Alterthum F, De Carvalho Lima LP. Some evidences for the hypothesis of active transport of streptomycin in Pseudomonas aeruginosa. Chemotherapy. 1976;22(6):341-5. - PubMed
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