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. 2020 Jun;81(6):263-264.
doi: 10.1016/j.humimm.2020.04.004. Epub 2020 Apr 18.

HLA-A, -B, -C, -DRB1 and -DQB1 alleles and haplotypes in 271 Southeast Asia Indians from Peninsular Malaysia

Ahmad Fauzi Nurul-Aain  1 , Lay-Kim Tan  2 , Hussein Heselynn  3 , Shahril Nor-Shuhaila  3 , Mageswaran Eashwary  3 , Sulaiman Wahinuddin  4 , Ing Soo Lau  5 , Suk Chyn Gun  6 , Mohamed-Said Mohd-Shahrir  7 , Mohd-Mokhtar Ainon  8 , Rosman Azmillah  5 , Othman Muhaini  9 , Murad Shahnaz  2 , Chun-Lai Too  10
Affiliations

HLA-A, -B, -C, -DRB1 and -DQB1 alleles and haplotypes in 271 Southeast Asia Indians from Peninsular Malaysia

Ahmad Fauzi Nurul-Aain et al. Hum Immunol. 2020 Jun.

Abstract

A total of 271 Southeast Asia Indians from Peninsular Malaysia were genotyped for HLA-A, -B, -C, -DRB1, and -DQB1 loci using polymerase chain reaction sequence-specific oligonucleotide probe hybridization methods. In this report, HLA-B and HLA-DQB1 was in Hardy-Weinberg proportions (HWEP) (p > 0.05). We observed significant deviation from the HWEP for HLA-A (p < 0.05), HLA-C (p < 0.01) and HLA-DRB1 (p < 0.01) loci. This genotype data is available in Allele Frequencies Network Database (AFND) Dos Santos et al. (2016).

Keywords: Alleles; HLA; Haplotypes; Peninsular Malaysia; Southeast Asia Indians.

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Conflict of interest statement

Declaration of Competing Interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.

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