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Comment
. 2020 Feb 17;20(2):105-107.
doi: 10.1177/1535759720901502. eCollection 2020 Mar-Apr.

The Beauty and the Dish: Brain Organoids Go Active

Alberto Sanchez-Aguilera, Liset Menendez de la Prida
Comment

The Beauty and the Dish: Brain Organoids Go Active

Alberto Sanchez-Aguilera et al. Epilepsy Curr. .
No abstract available

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Figures

Figure 1.
Figure 1.
Organoid and organotypic preparations of the human brain are revolutionizing biomedical research. Stem cell–derived organoids plated over multielectrode arrays allow studying physiopathological aspects of many neurological conditions. Whenever possible, they can be combined with organotypic cultures of human brain surgical samples, such as in cases of epilepsy or brain tumors. Both preparations can be functionalized with novel cell-type-specific opto- and chemogenetic approaches to test the physiological impact of novel genetic and pharmacological therapeutic approaches in a more personalized way. Illustrated by Andrea Navas-Olive.
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