Glucose Metabolism Takes Center Stage in Epithelial-Mesenchymal Plasticity
- PMID: 32315608
- DOI: 10.1016/j.devcel.2020.03.021
Glucose Metabolism Takes Center Stage in Epithelial-Mesenchymal Plasticity
Abstract
Aerobic glycolysis, or Warburg effect, has been associated with pathologies such as cancer. In this issue of Developmental Cell, Bhattacharya et al. show that aerobic glycolysis is required for neural crest migration in development. These findings point to a link between glucose metabolism and epithelial-mesenchymal plasticity in development and disease.
Copyright © 2020 Elsevier Inc. All rights reserved.
Comment on
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Metabolic Reprogramming Promotes Neural Crest Migration via Yap/Tead Signaling.Dev Cell. 2020 Apr 20;53(2):199-211.e6. doi: 10.1016/j.devcel.2020.03.005. Epub 2020 Apr 2. Dev Cell. 2020. PMID: 32243782 Free PMC article.
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