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. 2020 Apr 16;25(8):1830.
doi: 10.3390/molecules25081830.

Atypical Lindenane-Type Sesquiterpenes from Lindera myrrha

Thuc-Huy Duong  1 , Mehdi A Beniddir  2 , Nguyen T Trung  3 , Cam-Tu D Phan  3 , Van Giau Vo  4   5 , Van-Kieu Nguyen  6   7 , Quynh-Loan Le  8 , Hoang-Dung Nguyen  8   9 , Pierre Le Pogam  2
Affiliations

Atypical Lindenane-Type Sesquiterpenes from Lindera myrrha

Thuc-Huy Duong et al. Molecules. .

Abstract

Two new lindenane sesquiterpenes were obtained from the roots of Lindera myrrha. These compounds were structurally elucidated by HRMS data, extensive NMR analyses, and comparison between experimental and theoretical 13C-NMR data. Myrrhalindenane A is the first monomeric seco-d lindenane displaying a non-rearranged, cyclohexanic C-ring. Myrrhalindenane B is the second occurrence of an angular lindenane-sesquiterpene related to a C6-C7 lactonization.

Keywords: DFT-NMR; Lindera; lindenane; sesquiterpene.

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Conflict of interest statement

The authors declare no conflict of interest.

Figures

Figure 1
Figure 1
Chemical structures of compounds 1 and 2.
Figure 2
Figure 2
COSY and key HMBC correlations of compounds 1 and 2.
Figure 3
Figure 3
Chemical structures of the four possible diastereoisomers of compound 1 along with their respective DP4 probabilities.
Figure 4
Figure 4
Chemical structures of the four possible diastereoisomers of compound 2 along with their respective DP4 probabilities.
See this image and copyright information in PMC

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