Prostate cancer visibility on multiparametric magnetic resonance imaging: high Gleason grade and increased tumour volume are not the only important histopathological features

Joseph M Norris^{1

2

3}, Lina M Carmona Echeverria^{1

3}, Benjamin S Simpson¹, Clare Allen⁴, Rhys Ball⁵, Alex Freeman⁵, Daniel Kelly⁶, Alex Kirkham⁴, Veeru Kasivisvanathan^{1

3}, Hayley C Whitaker¹, Mark Emberton^{1

2}

Affiliations

¹ UCL Division of Surgery and Interventional Science, University College London, London, UK.
² London Deanery of Urology, London, UK.
³ Department of Urology, University College London Hospitals NHS Foundation Trust, London, UK.
⁴ Department of Radiology, University College London Hospitals NHS Foundation Trust, London, UK.
⁵ Department of Pathology, University College London Hospitals NHS Foundation Trust, London, UK.
⁶ School of Healthcare Sciences, Cardiff University, Wales, UK.

Comment

Joseph M Norris et al. BJU Int. 2020 Aug.

. 2020 Aug;126(2):237-239.

doi: 10.1111/bju.15085. Epub 2020 May 18.

¹ UCL Division of Surgery and Interventional Science, University College London, London, UK.
² London Deanery of Urology, London, UK.
³ Department of Urology, University College London Hospitals NHS Foundation Trust, London, UK.
⁴ Department of Radiology, University College London Hospitals NHS Foundation Trust, London, UK.
⁵ Department of Pathology, University College London Hospitals NHS Foundation Trust, London, UK.
⁶ School of Healthcare Sciences, Cardiff University, Wales, UK.

No abstract available

Comment on

Histological differences in cancer cells, stroma, and luminal spaces strongly correlate with in vivo MRI-detectability of prostate cancer.
Miyai K, Mikoshi A, Hamabe F, Nakanishi K, Ito K, Tsuda H, Shinmoto H. Miyai K, et al. Mod Pathol. 2019 Oct;32(10):1536-1543. doi: 10.1038/s41379-019-0292-y. Epub 2019 Jun 7. Mod Pathol. 2019. PMID: 31175330

1. Ahmed HU, El-Shater Bosaily A, Brown LC et al. Diagnostic accuracy of multi-parametric MRI and TRUS biopsy in prostate cancer (PROMIS): a paired validating confirmatory study. Lancet 2017; 389: 815-22
1. Miyai K, Mikoshi A, Hamabe F et al. Histological differences in cancer cells, stroma, and luminal spaces strongly correlate with in vivo MRI-detectability of prostate cancer. Mod Pathol 2019; 32: 1536-43
1. Borren A, Groenendaal G, Moman MR et al. Accurate prostate tumour detection with multiparametric magnetic resonance imaging: dependence on histological properties. Acta Oncol 2014; 53: 88-95
1. Schieda N, Coffey N, Gulavita P, Al-Dandan O, Shabana W, Flood TA. Prostatic ductal adenocarcinoma: an aggressive tumour variant unrecognized on T2 weighted magnetic resonance imaging (MRI). Eur Radiol 2014; 24: 1349
1. Truong M, Feng C, Hollenberg G et al. A comprehensive analysis of cribriform morphology on magnetic resonance imaging/ultrasound fusion biopsy correlated with radical prostatectomy specimens. J Urol 2018; 199: 106-13