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Case Reports
. 2020 Jul;20(7):1925-1929.
doi: 10.1111/ajt.15932. Epub 2020 Jun 11.

A case of SARS-CoV-2 pneumonia with successful antiviral therapy in a 77-year-old man with a heart transplant

Daniel Mathies  1 , Dominic Rauschning  1 , Ulrike Wagner  1 , Frank Mueller  1 , Maja Maibaum  1 , Christin Binnemann  1 , Stephan Waldeck  2 , Katrin Thinnes  3 , Michael Braun  3 , Willi Schmidbauer  3 , Ralf M Hagen  4 , Christoph Bickel  1
Affiliations
Case Reports

A case of SARS-CoV-2 pneumonia with successful antiviral therapy in a 77-year-old man with a heart transplant

Daniel Mathies et al. Am J Transplant. 2020 Jul.

Abstract

The SARS-CoV-2 infection can be seen as a single disease, but it also affects patients with relevant comorbidities who may have an increased risk of a severe course of infection. In this report, we present a 77-year-old patient with a heart transplant receiving relevant immunosuppressive therapy who tested positive for SARS-CoV-2 after several days of dyspnea, dry cough, and light general symptoms. Computed tomography confirmed interstitial pneumonia. The patient received antiviral therapy with hydroxychloroquine and showed no further deterioration of the clinical state. After 12 days of hospitalization, the patient was released; he was SARS-CoV-2 negative and completely asymptomatic.

Keywords: antibiotic: antiviral; clinical research/practice; heart transplantation/cardiology; immunosuppressant - calcineurin inhibitor: tacrolimus; immunosuppression/immune modulation; infection and infectious agents - viral; infectious disease; lung disease: infectious; off-label drug use.

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Figures

FIGURE 1
FIGURE 1
Cross-sectional view of the thorax computed tomography scan (maximum intensity projection) with diffuse opaque infiltration and a color-coded analysis of the segmental perfusion mismatch [Color figure can be viewed at wileyonlinelibrary.com]
FIGURE 2
FIGURE 2
Schematic summary of the course of disease [Color figure can be viewed at wileyonlinelibrary.com]
See this image and copyright information in PMC

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