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Comment
. 2020 May 8;12(5):e12059.
doi: 10.15252/emmm.202012059. Epub 2020 Apr 22.

Viruses to fight other viruses: the influenza vaccine case

Jose A Bengoechea  1
Affiliations
Comment

Viruses to fight other viruses: the influenza vaccine case

Jose A Bengoechea. EMBO Mol Med. .

Abstract

Undoubtedly, vaccination is one of the health interventions showing major impact on humankind. Vaccines remain one of the most effective and safest ways to tackle infections. The current coronavirus pandemic is not an exception, and we all hope that ongoing international efforts will succeed in developing a vaccine soon. In this scenario, the present work published in this edition of EMBO Molecular Medicine by Demminger and colleagues (Demminger et al, 2020) is timeliness to exemplify the steps needed to develop effective vaccines.

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Figures

Figure 1
Figure 1. Schematic of the research approach followed to develop AAV vectors as vaccine candidates against influenza
After developing AAV vectors expressing influenza surface exposed antigens, authors followed an elegant pipeline probing their vectors first in mice and subsequently in ferrets, research model that accurately recapitulates human influenza infections. Vaccines were administered via the intranasal route, key to develop protective antibodies.
See this image and copyright information in PMC

Comment on

References

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