IL6-R blocking with tocilizumab in critically ill patients with hemophagocytic syndrome
- PMID: 32321563
- PMCID: PMC7175448
- DOI: 10.1186/s13054-020-02878-7
IL6-R blocking with tocilizumab in critically ill patients with hemophagocytic syndrome
Keywords: HLH; Hemophagocytic lymphohistiocytosis; IL-6; Tocilizumab.
Conflict of interest statement
The authors have no conflicts of interest to disclose.
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Comment on
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Recommendations for the management of hemophagocytic lymphohistiocytosis in adults.Blood. 2019 Jun 6;133(23):2465-2477. doi: 10.1182/blood.2018894618. Epub 2019 Apr 16. Blood. 2019. PMID: 30992265
References
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- La Rosée P, Horne AC, Hines M, Greenwood TVB, Machowicz R, Berliner N, et al. Recommendations for the management of hemophagocytic lymphohistiocytosis in adults. Blood Ame Soc Hematol. 2019;133:2465–2477. - PubMed
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- Faguer S, Vergez F, Peres M, Ferrandiz I, Casemayou A, Belliere J, et al. Tocilizumab added to conventional therapy reverses both the cytokine profile and CD8+Granzyme+ T-cells/NK cells expansion in refractory hemophagocytic lymphohistiocytosis. Hematol Oncol. 2016;34(1):55–7. - PubMed
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