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Review
. 2020 Apr 13;6(4):e03690.
doi: 10.1016/j.heliyon.2020.e03690. eCollection 2020 Apr.

Childhood diarrhoeal diseases in developing countries

Harriet U Ugboko  1 , Obinna C Nwinyi  1 , Solomon U Oranusi  1 , John O Oyewale  1
Affiliations
Review

Childhood diarrhoeal diseases in developing countries

Harriet U Ugboko et al. Heliyon. .

Erratum in

Abstract

Diarrhoeal diseases collectively constitute a serious public health challenge globally, especially as the leading cause of death in children (after respiratory diseases). Childhood diarrhoea affecting children under the age of five accounts for approximately 63% of the global burden. Accurate and timely detection of the aetiology of these diseases is very crucial; but conventional methods, apart from being laborious and time-consuming, often fail to identify difficult-to-culture pathogens. The aetiological agent of an average of up to 40% of cases of diarrhoea cannot be identified. This review gives an overview of the recent trends in the epidemiology and treatment of diarrhoea and aims at highlighting the potentials of metagenomics technique as a diagnostic method for enteric infections.

Keywords: Childhood; Diagnostics; Diarrhoea; Epidemiology; Medical microbiology; Metagenomics; Microbiology; Microbiology epidemiology; Molecular biology; Therapy.

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Figures

Figure 1
Figure 1
Causes of child deaths worldwide; Source: Liu et al. (2012)..
Figure 2
Figure 2
Data showing the high rate of diarrhoea morbidity among children below 5 years in Nigeria and some Asian Countries. Source: Computed by the Researcher with data from https://data.unicef.org/topic/child-health/diarrhoeal-disease/Accessed 17th February 2019.
See this image and copyright information in PMC

References

    1. Abuzerr S., Nasseri S., Yunesian M., Hadi M., Zinszer K., Mahvi A.H., Mohammed S.H. Water, sanitation, and hygiene risk factors of acute diarrhea among children under five years in the Gaza Strip. J. Water, Sanit. Hyg. Dev. 2020;10(1):111–123.
    1. Adam M.A., Wang J., Enan K.A., Shen H., Wang H., El Hussein A.R. Molecular survey of viral and bacterial causes of childhood diarrhea in Khartoum state, Sudan. Front. Microbiol. 2018;9:112. - PMC - PubMed
    1. Agholi M., Hatam G.R., Motazedian M.H. HIV/AIDS-associated opportunistic protozoal diarrhea. AIDS Res. Hum. Retrovir. 2013;29(1):35–41. - PMC - PubMed
    1. Ahmad N., Drew W.L., Plorde J.J. fifth ed. McGraw-Hill Companies; USA: 2010. Sherris Medical Microbiology; pp. 929–931.
    1. Aiemjoy K., Altan E., Aragie S., Fry D.M., Phan T.G., Deng X. Viral species richness and composition in young children with loose or watery stool in Ethiopia. BMC Infect. Dis. 2019;19(1):53. - PMC - PubMed